Home Cosmetic Science Talk Formulating Dosing from in Vitro to In Vivo

  • Perry44

    September 25, 2023 at 7:46 am

    I suppose that depends on the claims you want to make. Let’s look at an example.

    Suppose you have an in vitro experiment that shows active X at 2% gives some benefit. Well if you want to claim that benefit in your product you should use it at 2% in your formula. At least you could make an argument it really could deliver that benefit.

    In truth, you should really test in vivo from your formula at the % actually used if you want to make the claim.

    But if you word your claim in the right way, you can put a tiny fraction of the ingredient in the final formula and simply imply that it will deliver some claim.

    But it would help if we had more information about the ingredient/benefit you are trying to deliver.

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