Home Cosmetic Science Talk Formulating Chemistry Question

  • Chemistry Question

    Posted by braveheart on January 1, 2015 at 6:49 am

    Can I combine L-ascorbic acid + magnesium chloride to achieve the stable form of Vitamin C, magnesium ascorbate , in a ratio 2:1?

    braveheart replied 9 years, 4 months ago 2 Members · 6 Replies
  • 6 Replies
  • Microformulation

    Member
    January 1, 2015 at 2:16 pm

    No, if I recall correctly you actually have to use a carbonate (Magnesium carbonate in this case) in an aqueous solution, then mill and dry the product. It also has to be assayed in a validated laboratory. After all that you get Magnesium ascorbate, a compound almost never used in skin care but more predominant in oral dosage forms. In the end it is more than a simple reaction as outlined in your question. Just buy some Magnesium Ascorbyl Phosphate (MAP) from Lotioncrafter and other such retail sites. In wholesale I know Charkit, Caribbean Naturals, and Uniproma sell MAP.

  • braveheart

    Member
    January 1, 2015 at 3:46 pm

    Thanks, do you think cosmetic or pharma grade is better?

    Since it can affect the dermis

    I am making my own VitaminC serum.
  • Microformulation

    Member
    January 1, 2015 at 9:06 pm

    If you are talking about a Vitamin C Serum, use the Cosmetic grade. Try not to go too crazy and try to match some high percentage of Vitamin C Net (what I call chasing the Perricone Dragon). Vitamin C derivatives plateau out and the higher percentages offer more topical side effects with blunted additional effect.

  • braveheart

    Member
    January 1, 2015 at 9:33 pm

    :)
    I agree 100%. Yes, I am gunning for the Vitamin C serum market and thinking of how to add my own twist to the industry. Looking at potential competitors, it seems they are sourced from the same manufacturer (which is great for the manufacturer), but with everyone trying to out-do each other with % in Vitamin C content. It looks quite interesting.

    Thanks for the tip.

  • Microformulation

    Member
    January 5, 2015 at 6:20 pm

    I have seen several and formulated several Vitamin C Serums. They are NOT all sourced through the same manufacturer but use similar concepts in the Formulation.

  • braveheart

    Member
    January 6, 2015 at 10:34 am

    oh ok. Thanks for the observation. It was that while checking out most of these companies, their labels look alike with the statement: “Manufactured in the US for….” That just left me wondering is it was the same source.

Log in to reply.