Home Cosmetic Science Talk Formulating Can silicones really provide occlusiveness to reduce Trans Epidermal Water Loss TEWL?

  • Can silicones really provide occlusiveness to reduce Trans Epidermal Water Loss TEWL?

    Posted by Gunther on November 13, 2019 at 6:08 pm

    It looks like silicones don’t:

    Results: Both petrolatum and silicones significantly decreased TEWL 15 min after application, but the measurements for the silicones were not significantly different from the untreated control values. The tested silicones did not moisturize the skin. Petrolatum formed an occlusive layer, creating an increase in skin hydration for more than 4 h. The results measured for the W/(O + Si) creams indicated that they moisturized the skin, without any effect on TEWL.
    Conclusion: A clear difference was shown between the skin occlusive properties of petrolatum and the water vapor permeability of the common silicone excipient materials.
    https://www.karger.com/Article/Abstract/354914

    Occlusivity

    …Most silicone fluids are recognized as non-occlusive. Some organically modified silicone products such as stearoxytrimethylsilane and stearyl alcohol do provide considerably greater occlusivity than mineral oil although significantly less than petrolatum.
    https://www.skinident.es/fileadmin/img/spanish-pictures/pdf/Silicones_as_Alternatives_to_Hydrocarbons.pdf

    Gunther replied 5 years ago 2 Members · 2 Replies
  • 2 Replies
  • Pharma

    Member
    November 13, 2019 at 7:51 pm
    That’s what I’ve learned too. Silicones ‘breath’, so to say.
    What’s your difference between mineral oil and petrolatum?
  • Gunther

    Member
    November 17, 2019 at 5:12 pm

    Pharma said:

    That’s what I’ve learned too. Silicones ‘breath’, so to say.
    What’s your difference between mineral oil and petrolatum?

    In my opinion petrolatum perceived moisturization feels so much better than mineral oil or silicones.

    Sensorials are different for all 3 above.
    So maybe you need Petrolatum to reduce TEWL and silicones to reduce soaping.

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