Home Cosmetic Science Talk Formulating Calculations in mg

  • Calculations in mg

    Posted by GreenFrog on April 24, 2018 at 1:49 pm

    Commonly working with percentages but this has thrown me for a loop as far as the calculations go.  I always think in the most complicated way first..I am not asking for anybody to do this for me but to help clear the confusion.

    How do I calculate the correct the right mg label claim for a 4 oz container of CBD? I think I am confusing myself for the most part. I know I want 300mg per 4 ounce container

    I have a CBD tincture that is 1500 mg in 1 oz.
    1500 mg / 29.5735 ml =25.3605 mg/mL

    Don’t I need to know the potency percentage of the CBD tincture? 

    GreenFrog replied 6 years ago 2 Members · 6 Replies
  • 6 Replies
  • Microformulation

    Member
    April 24, 2018 at 5:37 pm

    You need the analysis of the CBD tincture giving you the yield of CBD.

    @BProvisons did an excellent breakdown of the process several weeks ago. https://chemistscorner.com/cosmeticsciencetalk/discussion/4067/cannabis-in-shampoo-and-conditioner#latest

  • GreenFrog

    Member
    April 25, 2018 at 4:32 am

    @BProvisions and @Microformulation
    I totally understand the point of view of each of you.  I must admit I have the same sentiment with heated conversations with non scientists.   This does not stop people for wanting to jump on the band wagon of a public trend right now.

    I just basically want to make sure I have right calculations for CBD alone. I have a tendency to make this more difficult than what it is.

    So lets just say my CBD potency is 75%. and I want to have a finish goods with 300 mg in a 4 ounce size of lotion.

    CBD available = 75% potent 

     

     

  • Microformulation

    Member
    April 25, 2018 at 9:11 am

    I doubt that the CBD is “75% potent” as this is really not how they report the testing. Somewhere I have a testing report from a lab in Oregon. If I can find it I will redact it and post later. Essentially it delineates the CBD per a volume of extract and the THC in a volume of extract. You then have to use this known extract breakdown to get the final concentration in the finished product. Without this testing result, the calculations are inaccurate and difficult.

    If you are going to do a product with any credibility, you must have a consistent product. My issue here is that on the surface we want to treat it as a credible medical product. If you want to do so you must treat the entire process as a quasi-pharmaceutical across the board. If you are not 100% behind this, just put in a small amount for label copy and move on.

    If you treat it as a credible product, you will need to use standard Pharmaceutical calculations. There are numerous resources to learn these online. I could weigh-in to help initially, but this is a skill you MUST learn as well. The difficulty in solving this immediately is that you don’t have all the factors. Essentially you have “solve for Y using X.” We know what Y should be, but you have no definition of X (the composition of the extract).

    Lastly, “This does not stop people for wanting to jump on the band wagon of a public trend right now,” is not the greatest argument to put forth. In my opinion, the people who will persevere in this Industry are the ones which do it right at the level of a credible product. Remember, lemmings running off a cliff into the ocean are also “following a popular public trend.”

  • GreenFrog

    Member
    April 25, 2018 at 12:18 pm

    @Microformulation
    I would be more than happy to look at a CBD potency report.  It would definitely help me.   I have every intention of learning this process. I do want credibility with the products and with my personal work.  That is why I am here since I am novice to this type of calculation.  I am not sure of all the parameters that I need to do this calculation. Right now I am working on getting more information about CBD that I am using.

  • Microformulation

    Member
    April 25, 2018 at 5:44 pm
  • GreenFrog

    Member
    April 26, 2018 at 2:54 am

    Thank you!  I will look at this and if I have any questions I will post ..

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