Best equipment for pharmaceutical formulation?
I’m wondering what would be the ideal equipment to use for a cough syrup formulation?
Between 65/85% Simple Syrup USP used as the main vehicle.
Methyl and Propyl Parabens used as preservatives.
Would a basic overhead stirrer suffice or should I be looking at high shear rotor/stator homogenisers?
Currently I’ve been testing different ingredients and proportions of ingredients with a basic laboratory magnetic hotplate stirrer however I do not feel this is working adequately.
Once bottled and left to sit I notice slight sedimentation which requires shaking to disperse.
Additionally prior to bottling I run the finished product through a filter sieve which also picks up sedimentation or undissolved/leftover particles. This is what makes me think a high shear homogenizer is what I need?
Thanks in advance for your help and suggestions!
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