• Formulating

  Benzoyl peroxide + Adapalene Gel

  Posted by amitvedakar on September 30, 2020 at 4:54 am

  I use Dimethyl isosorbide to dissolve benzoyl peroxide for making.gel.

  Is there any other solublizer for Benzoyl Peroxide?

  I made ADAPALNE+ Benzoyl Peroxide gel,but it’s yellowish. Any suggestion.

  I know this is pharma formulation question.

  But required help for this formulation.

  My benzoyl peroxide plain gel is white dissolved in DMI.

  market products contains docusate sodium & POLOXAMER.

  I could not find info/role of these two ingredients 

  Can any one Help?

  amitvedakar replied 3 years, 4 months ago 2 Members · 3 Replies
• 3 Replies

• 

  amitvedakar

  Member

  December 28, 2020 at 5:19 am

  I found the culprit. BHT/BHA. most probably BHA.

• 

  chemicalmatt

  Member

  December 28, 2020 at 9:37 pm

  Good call @amitvedakar: should not mix an oxidizer with an anti-oxidant. Defeats the purpose, right? 

• 

  amitvedakar

  Member

  December 30, 2020 at 4:57 am

  yes Sir, @chemicalmatt . Thank you.

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