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Autoclaving potassium sorbate stock
According to this, potassium sorbate solution can be autoclaved to be sterilized.
https://pharmacentral.com/product/potassium-sorbate-pharmaceutical-preservative/
If there’s no concern, I’d like to autoclave my stock solution.
Does anyone know something that contradicts this or would point that autoclaving potassium sorbate would lead to a meaningful loss of activity or in any way, bad?
For instance, sucrose solution can be autoclaved, but it does lead to caramelization so while it is autoclavable, I know filter-sterilization if preferred. Similarly I am wondering whether there’s a reason not to autoclave potassium sorbate as I haven’t really read people actively autoclaving this.
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3 Replies
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Why would you autoclave?
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why not.
Just kidding, because that itself can be the source of bacteria.
You can say “but don’t you add antibacterial preservative anyway?”
But I have a specific reason why I want this separately sterile.
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Agree - the solution is at risk for contamination. You could get a rough idea by comparing ZOI - before and after autclaving.
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