MemberJuly 10, 2021 at 11:34 pmGraillotion said:Graillotion said:@Grallotion:
Yes, I think a CBD extract of any type would be better than CBD isolate. I’ve worked with both, and while I don’t believe the “entourage effect” has been proven to be true, using CBD isolate completely eliminates any possibility of synergistic effects between the various components of a CBD extract.
Are you saying….the only drawback to the CBD isolate (vs CBD extract)…is the lack of secondary components? (I can live with that.)
Where I have been buying my CBD isolate…they also sell CBN, CBG, and CBC. With pain in mind…if I were to blend one of these in…which would you choose?
I would use a combination of CBD and CBG
I find it about impossible to find dosing for the cannabinoids (this of course is intentional), so any idea on dosing for a cream? I am using 1% of CBD Isolate….I assume I will keep that the same, and just add some CBG. Since it is a pricey ingredient (more than double the cost of CBD), what level would I have to include to hopefully create an effect?
Obviously inclusion rate hinges on potency….so let’s use this as an example:
You formulate CBD products to a target load of CBD (or CBG) in milligrams per unit. It looks like you’re making a cream with 1,000 mg CBD, which is a good strength for a pain management product. It’s completely up to you on the strength. You might do 1,000 mg CBD + 200 - 400 mg CBG, for instance.
Thank you for your helpful insights Mark. In this scenario, as a pain cream formulator, I am very hamstrung by not suffering from any type of chronic pain, thereby eliminating myself as a test subject. Do you have anyone in-house (literally and figuratively) that suffers pain that a cream like this might mitigate? I am always looking for test subjects that can provide quality feedback. If so, I would love to send you a sample. You can PM me…with address.
This is not a half-a$$ formula….it is made with watchful oversight and input from someone I believe you respect, someone who’s PhD focused on phytochemistry and pharmacognosy.
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