0.3% retinol in isopropyl Myristate stability - Chemists Corner

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0.3% retinol in isopropyl Myristate stability

Posted by Abdullah on July 16, 2021 at 4:04 pm

Does 0.3% retinol in isopropyl Myristate or CCT make a stable form of retinol product?

Abdullah replied 2 years, 9 months ago 2 Members · 4 Replies
4 Replies

ngarayeva001

Member
July 16, 2021 at 6:54 pm

Retinol is often supplied in CCT + antioxidants
Abdullah

Member
July 17, 2021 at 4:19 pm

ngarayeva001 said:

Retinol is often supplied in CCT + antioxidants

Thanks
Will it be stable if we don’t add antioxidants?
ngarayeva001

Member
July 18, 2021 at 2:55 pm

It won’t be stable even if you add antioxidants and keep it in freezer. Retinol is utterly unstable. I am talking about actual retinol not derivatives. Tretinoin is even worse.
Abdullah

Member
July 18, 2021 at 3:24 pm

ngarayeva001 said:

It won’t be stable even if you add antioxidants and keep it in freezer. Retinol is utterly unstable. I am talking about actual retinol not derivatives. Tretinoin is even worse.

What makes retinol unstable?
Water

Air

Heat

Light
Or something else?

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