Home Cosmetic Science Talk Formulating Glyceryl Stearate inhibiting the function of ferulic acid??

  • Glyceryl Stearate inhibiting the function of ferulic acid??

    Posted by BIOCHM73 on October 26, 2022 at 4:44 pm

    I finished a skin brightening formula that has Ferulic Acid as a functional for skin brightening, but the customer (an esthetician) emailed us and said that she “read that glyceryl stearate inhibits the efficacy of Ferulic Acid”. I have checked a bunch of resources and did not see any information on this. Any ideas?

    Microformulation replied 1 year, 10 months ago 5 Members · 6 Replies
  • 6 Replies
  • suswang8

    Member
    October 30, 2022 at 4:33 am

    Stating the obvious here, but why not ask her to please send you the link to where she read this as you have not been able to find anything to corroborate that?

  • OldPerry

    Member
    October 31, 2022 at 4:19 pm

    Stating the less-than-obvious, how could anyone know whether it inhibited the function of ferulic acid or not? There is little evidence that ferulic acid does anything anyway!

    I can confidently declare using Glyceryl Stearate with Ferulic Acid will make exactly zero noticeable difference in performance.

  • Microformulation

    Member
    October 31, 2022 at 8:24 pm
  • OldPerry

    Member
    October 31, 2022 at 9:10 pm

    @Microformulation - interesting work. And suggests there won’t be any chemical reaction between the acid and glyceryl stearate.

    But the authors go in with the assumption that ferulic acid does something in a topical treatment. I don’t think that has been proven.

  • Pharma

    Member
    November 1, 2022 at 5:35 am
    The interaction found in that publication is with Optiphen, not with GMS ;) . And FTIR alone is no proof, just an indication.
    It’s a poorly made publication, too.
  • Microformulation

    Member
    November 1, 2022 at 11:49 am

    Pharma said:

    The interaction found in that publication is with Optiphen, not with GMS ;) . And FTIR alone is no proof, just an indication.
    It’s a poorly made publication, too.

    I agree 100%. I am imagining someone misinterpreted the findings of this study for marketing. We have seen this so many times in the past.
    No intended offense to any Esthetician, but I have been asked to speak at Cosmetology Schools before (never again), and the misconceptions in these Forums were remarkable.

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