Home Cosmetic Science Talk Formulating 0.3% retinol in isopropyl Myristate stability

  • ngarayeva001

    Member
    July 16, 2021 at 6:54 pm

    Retinol is often supplied in CCT + antioxidants 

  • Abdullah

    Member
    July 17, 2021 at 4:19 pm

    Retinol is often supplied in CCT + antioxidants 

    Thanks 
    Will it be stable if we don’t add antioxidants?

  • ngarayeva001

    Member
    July 18, 2021 at 2:55 pm

    It won’t be stable even if you add antioxidants and keep it in freezer. Retinol is utterly unstable. I am talking about actual retinol not derivatives. Tretinoin is even worse.

  • Abdullah

    Member
    July 18, 2021 at 3:24 pm

    It won’t be stable even if you add antioxidants and keep it in freezer. Retinol is utterly unstable. I am talking about actual retinol not derivatives. Tretinoin is even worse.

    What makes retinol unstable? 
    Water

    Air
    Heat
    Light 
    Or something else? 

Log in to reply.

Chemists Corner