Members Directory - Chemists Corner

ZleyHoldings

Member

February 4, 2021 at 6:37 am in reply to: Does this require a preservative?

Chlorphenesin CAS: 104-29-0 Maximum dosage: 0.3%
P-hydroxyacetophenone CAS: 99-93-4 Recommended dosage: 0.5 - 1%

This is the preservative formula we tested：
0.224% 1,2-hexanediol,

0.056% ethylhexylglycerol,
0.056% caprylohydroxamic acid,
0.084% glyceryl caprylate,

total addition of 0.42%

ZleyHoldings

Member

February 4, 2021 at 6:15 am in reply to: Storing Preservatives

We produce Chlorphenesin CAS: 104-29-0, P-hydroxyacetophenone CAS: 99-93-4, Caprylhydroxamic acid CAS: 7377-03-9, and Capryloyl Glycine CAS: 14246-53-8 which are all very good cosmetic preservatives, they are in powder form and can be stored at room temperature for up to 3 years.

Say goodbye to the fridge

ZleyHoldings

Member

December 25, 2020 at 6:16 am in reply to: Merry Christmas to everyone!

The bad 2020 is almost over!!!

ZleyHoldings

Member

November 17, 2020 at 5:00 am in reply to: What preservatives do you use most often?

Perry said:

@ZleyHoldings - While you may “feel” DMDM and isothiazolinones can be harmful to the body, this is not based on scientific evidence. These ingredients have been proven to be safe for use in the way they are used in cosmetics.

If you base your preservative choices on feelings, I’m afraid chlorphenesin won’t make the cut with some consumers. For example, https://www.annmariegianni.com/ingredient-watch-list-chlorphenesin-the-synthetic-preservative-that-can-cause-dermatitis-and-infant-respiratory-distress/

Neither will Carpylhydroxamic acid since it is causing “an epidemic of allergic contact dermatitis” - https://pubmed.ncbi.nlm.nih.gov/28421670/

Traditional preservatives can be used safely. If formulators avoid them and buy into “fear marketing” there aren’t going to be any effective preservatives left.

Okay, thanks. I’ll check the information carefully.

ZleyHoldings

Member

November 13, 2020 at 2:36 am in reply to: What preservatives do you use most often?

Bill_Toge said:

in a previous job I’d use DMDM hydantoin or isothiazolinones for rinse-off products, or Euxyl PE9010 for leave-on products, plus DMDM hydantoin if there were a lot of suspended solids in the product, e.g. clays

as it stands, I am restricted to Dermosoft 1388 and GMCY, keeping the pH below 6 if there are suspended solids in the product; propanediol at 10-20% helps as well

in fairness, it works well; thanks to a robust preservative system, and a reliable supply of clean sterilised mains water, it’s very rare for us to have a micro count on any of our products

Thanks, but our country has started to reduce the use of DMDM hydantoin and isothiazolinones. Because we feel they can be harmful to the body. Now we are more and more starting to use safer preservatives like chlorphenesin, p-hydroxyacetophenone, and Caprylhydroxamic acid.

ZleyHoldings

Member

November 11, 2020 at 2:39 am in reply to: What preservatives do you use most often?

Pharma said:

- Methyl- & Propylparaben or sodium benzoate & potassium sorbate for pharmaceutical preparations (made on prescription at the pharmacy)

- Verstatil PC (phenoxyethanol & caprylyl glycol) for trial formulations

- Dermosoft 1388 eco (sodium levulinate & sodium anisate) plus glyceryl caprylate plus pentylene glycol plus Magnolia Extract 98 for everything else. Stupid thing is, that cocktail seems to negatively affect viscosity and even break certain emulsions.

Obviously, I also add a chelate (phytic acid or EDTA) and antioxidants (different ones, depending on requirements).

That’s very detailed, thank you.

ZleyHoldings

Member

November 11, 2020 at 2:38 am in reply to: What preservatives do you use most often?

Belassi said:

Sodium benzoate for hair products, KEM NAT for skin products.

Thank You.

ZleyHoldings

Member

November 11, 2020 at 2:38 am in reply to: What preservatives do you use most often?

Perry said:

DMDM Hydantoin

Thank You :p

ZleyHoldings

Member

November 11, 2020 at 2:37 am in reply to: What preservatives do you use most often?

ngarayeva001 said:

Phenonip and germall plus (depends on the product)

Thank You

ZleyHoldings

Member

November 11, 2020 at 2:37 am in reply to: What preservatives do you use most often?

Fekher said:

@ZleyHoldings Cathon CG and Euxyl

Thank You

ZleyHoldings

Member

October 27, 2020 at 2:42 am in reply to: Antioxidant preservative

You can try our chlorphenesin, caprylhydroxamic acid, and p-hydroxyacetophenone.

You can contact me.

ZleyHoldings

Member

October 27, 2020 at 2:38 am in reply to: Broad spectrum preservatives for ‘green’ marketing

You can try our Chlorphenesin, Caprylohydroxamic acid, p-hydroxyacetophenone.

https://www.ulprospector.com/en/na/PersonalCare/Suppliers/110295/Zley-Holdings-Suzhou-Co-Ltd

ZleyHoldings

Member

July 17, 2020 at 1:16 am in reply to: Suppliers for small quantities in Mexico

Belassi said:

@ZleyHoldings Very nice of you to offer. Just one note: If sending anything to Mexico it should be via post, not via courier such as DHL or FEDEX. This is because of the onerous customs clearance problem. I’ve successfully ordered materials (eg. glycrrhizic acid) from China in small quantities (up to 5Kg) by post.

wow, ！It’s so cool
Usually, we use DHL, Fedex and UPS as you mentioned. If the demand is high, we will choose container shipping.