PhilGeis
Forum Replies Created
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Gluconate is not a good substitute for EDTA.
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You need not immerse small pieces . Spray, ensuring you hit all surfaces, and do watch for vapor buildup.
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Some consider the 70% to be self preserving.
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You must clean before sanitizing
70-75% - prefer ethanol
before each batching
let it evaporate - acts in seconds
cover small items after sanitizingit is an explosion hazard so be aware of vapor buildup
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Can’t use sal acid on kids under 3 per EU cosm. directive.
If you use an organic acid, make is benzoic (as Na salt).
I’d put phenoxyethanol behind isothiazolinones and DMM hydantoin.
Add a chelant - esp. EDTA. -
I’ll add another case study. Soap shipped as prills in fiber drums suffered gross mold contamination. As bar it never had any issue. Difference was water activity - greater surface area for evaporation in a closed vessel increased Aw to permissive level for fungal growth on (high pH) prills.
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It does Bill but is effective vs. manufacturing risk. Consumer use is not relevant. It doesn’t need to be that stable.
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Sorry - I don’t know. You could run a diffusion study to semquantify pres stability.
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Clay is hard to preserve and chelants do poorly with it. DMDM hydantoin with parabens or an organic acid (if pH permits) would be a reasonable try.
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I think I answered the central question.
pH 3-8 is not an adequate standard and soap can be contaminated - esp. with additions such as milk. Obviously relevant contaminant has special capabilities.I’ll add my 1st experience was with a well known French milk bar in the early “80 prob with the same bug - Nesterenkonia wasn’t named until 1995
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There are preservatives in this ingredient list. Preservative is there because it is needed. Soap, esp. with milk, can be contaminated and the pH is not necessarily enough to protect.
You’d need a pH of ~2 or less and ~11 or greater to assure protectionhttps://onlinelibrary.wiley.com/doi/abs/10.1111/ics.12401
and
Prevalence of Moderately Halophytic
Aerobic Gram Positive Cocci in Bath
Soap Bars with Special Reference to
Nesterenkonia -
Don’t store -it’s not that stable.
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probably - keep pH neutral or slightly acidic
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In what form is your finished product - solid/liquid/gel?
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There also better than the odd combination
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You can use combinations of others based on pH but would need testing
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I referred to active concentration.
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2000-3000 ppm is what I’d use
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Matt - correction - think it was Oxadine A
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What is the product?
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It’s not so much the time/kinetics as continued wetness hopefully gets into cracks, crevices etc. There’s no way to know if that’s effectively accomplished - I’d stick with longer time.
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Hey Matt! Introduced back in late 70’s by Angus, think it was formaldehyde releaser “Oxiban A”. worked pretty well.
Germall et al. already had the role so never got a foothold in the market. Recall only one product that used it back then - (don’t laugh) - Brylcreme. -
Make sure it’d clean 1st and try to not let the sanaitizing solution dry. Repeat spraying enough to keep it wet/damp.
Long term - as your business grows, consider a plan to implement https://www.fda.gov/cosmetics/cosmetics-guidance-documents/good-manufacturing-practice-gmp-guidelinesinspection-checklist-cosmetics. -
Keep it wetted.
Do you have a longer term strategy to lower micro risk? -
Use at least 2500 ppm - but parabens prob better.