Forum Replies Created

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  • OldPerry

    Professional Chemist / Formulator
    September 25, 2020 at 3:44 pm in reply to: CMV - Methylisothiazolinone preservatives are safe for rinse-off products

    @Belassi - you’re certainly not alone in having experienced negative reactions. I agree that for people who do have bad reactions to it, it is an ingredient they should avoid. I haven’t seen any data on dogs but don’t doubt that it could be a problem.

    However, people have reactions to all kinds of raw materials used in cosmetics.  For example, SLS, glucosides, organic acids, plant extracts, etc.

    What is the criteria by which we decide when a reaction effects enough people that the ingredient is banned from products?

  • OldPerry

    Professional Chemist / Formulator
    September 25, 2020 at 2:12 pm in reply to: Shampoo Lather

    @ajw000 - In the testing I did with the ingredient on hair tresses, I never saw that effect.

  • OldPerry

    Professional Chemist / Formulator
    September 25, 2020 at 1:32 pm in reply to: which preservative would you choose?

    Nearly all preservatives have restrictions in different places in the world. So, it’s not surprising that DMDM has restrictions on it. Use it within the restricted levels and you’ll be fine.

    But to your question, here is what you use as an important selection factor.

    Most important
    1.  Is it compatible with your ingredients?
    2.  Is it effective in your system?

    Important
    3.  Price
    4.  Can you get a reliable supply?
    5.  Does it go well with your marketing story?

    For your specific case, I think you just have to try both and see what works better.

  • OldPerry

    Professional Chemist / Formulator
    September 24, 2020 at 2:32 pm in reply to: Dimethicone vs Cyclomethicone for anti-soaping and skin feel?

    @ngarayeva001 - it evaporates so in that sense…it expires. But it likely won’t break down much over time.

  • OldPerry

    Professional Chemist / Formulator
    September 24, 2020 at 2:32 pm in reply to: DIY Hair Shampoo but make scalp itchy

    Glycerin will also kill your foam. There is no reason to use it.
    Panthenol isn’t doing much in your formula either. 1% is way too high. It’s a claims ingredient.

    You didn’t give the % Activity of the surfactants so it’s difficult to know if it is too high.  But 35% surfactant is too high and could cause the itching.

    7% Dimethiconol is much higher than companies would use. It is also going to kill your foam. You don’t need more than 1%.

    I’ll finish by saying that it’s unlikely that Sulfate shampoos were causing your hair to fall out. There is no evidence that they  do that.

  • OldPerry

    Professional Chemist / Formulator
    September 24, 2020 at 2:26 pm in reply to: Stabilizer in emulsions/creams

    I guess that depends on what type of ingredients you are talking about.
    Carbomer is compatible with non ionic materials. It can also be compatible with anionic materials.  It just doesn’t work well with certain ions like salts. And it has to be neutralized.  But lots of cream emulsions are stabilized with Carbomer.

  • OldPerry

    Professional Chemist / Formulator
    September 23, 2020 at 9:14 pm in reply to: Stabilizer in emulsions/creams

    Carbomer is added to the water before adding any other ingredient.

  • OldPerry

    Professional Chemist / Formulator
    September 23, 2020 at 2:49 pm in reply to: Raw Materials Expiration Dates

    I’ve written on this subject.  See here.

    Cosmetic ingredient expiration date

  • OldPerry

    Professional Chemist / Formulator
    September 23, 2020 at 12:35 pm in reply to: Stabilizer in emulsions/creams

    Carbomer.  0.2%
    But what you use and how much depends on what else is in the formula.

  • OldPerry

    Professional Chemist / Formulator
    September 23, 2020 at 2:24 am in reply to: Shampoo Lather

    @Belassi - There is one other use. Some consumers find it a compelling marketing story.

  • OldPerry

    Professional Chemist / Formulator
    September 22, 2020 at 2:11 pm in reply to: Is it legal to sell cosmetics with ketoconazole?

    No, that is legal.  It is an OTC product and they follow the manufacturing requirements of the OTC monograph for antidandruff products.

    If you follow all the requirements for producing an OTC drug as outlined in the monograph ( https://www.fda.gov/drugs/status-otc-rulemakings/rulemaking-history-otc-dandruff-seborrheic-dermatitis-and-psoriasis-drug-products ) then it is perfectly legal to sell the products.

    If you take a drug active, mix it into your cosmetic formula and start selling it online, that would be illegal.

  • OldPerry

    Professional Chemist / Formulator
    September 22, 2020 at 1:41 pm in reply to: Surgical Handwash

    You might check for groups on LinkedIn.

    Or if there is a professional society for Microbiology or Pharmacology you can see if they have a forum.

    In truth, a forum like this is an anomaly. There aren’t a lot of industry specific forums because the people with the expertise work for companies and are often not allowed to share information. 

  • OldPerry

    Professional Chemist / Formulator
    September 22, 2020 at 1:38 pm in reply to: Need help understanding the process of hiring a chemist

    @jones7216 - what you want is a Contract Manufacturer and maybe more specifically a Fragrance House. You can find those types of companies here.
    https://www.happi.com/contract-manufacturing-private-label-directory/all_companies/

  • OldPerry

    Professional Chemist / Formulator
    September 22, 2020 at 1:35 pm in reply to: Is it legal to sell cosmetics with ketoconazole?

    People break the law.

    Amazon doesn’t police their platform very well & they make money from illegal drug sales, so unless there is some government agency going after them they ignore it. 

    The FDA resources are spread so thin that they can’t go after every company on the Internet selling illegal drugs.

    These companies eventually get shut down. The people involved, lay low for a while, then start a new LLC, and start selling again until they get caught. Rinse and repeat. In the meantime, unwitting consumers assume anything on Amazon is legal and keep spending their money.

  • OldPerry

    Professional Chemist / Formulator
    September 21, 2020 at 10:07 pm in reply to: Is it legal to sell cosmetics with ketoconazole?

    No, it is not legal. Ketoconazole is a drug active.  A prescription is required thus making it illegal to sell as a cosmetic.

  • OldPerry

    Professional Chemist / Formulator
    September 21, 2020 at 10:02 pm in reply to: Question regarding Lip Gloss and Preservatives

    Yes, that one should work.

  • OldPerry

    Professional Chemist / Formulator
    September 21, 2020 at 5:47 pm in reply to: Question regarding Lip Gloss and Preservatives

    I personally think you should add one.

    There is almost no downside to including a preservative, and it will protect users from the off chance that the moisture from their lips creates an environment on and in your product in which microbes could grow. 

  • OldPerry

    Professional Chemist / Formulator
    September 21, 2020 at 1:19 pm in reply to: Fragrance survey……

    Only your customers can answer this but in general, I’d go with what is most popular on the market. Then let your marketing and brand story make the sales for you. Very few people find the performance of a product so compelling that they don’t want to try anything else. Brand loyalty is built through the brand story.

  • OldPerry

    Professional Chemist / Formulator
    September 20, 2020 at 1:48 pm in reply to: Can I get opinions on the below clarifying shampoo formula for African hair?

    Also, you probably don’t need the xanthan gum. You could adjust the viscosity using sodium chloride (salt).

  • OldPerry

    Professional Chemist / Formulator
    September 20, 2020 at 1:28 pm in reply to: Should we increase the conditioner in this Shampoo?

    @Abdullah - it’s the way in which cationic polymers are left behind on the hair. The theory is this. Cationic polymers are made soluble in surfactant solutions that are concentrated (as in a shampoo). When the product is in use, it is diluted with water. That reduces the solution to the level at which the cationic polymer is no longer soluble. For this reason, it plates out onto the hair and is not washed away. 

    For conditioning agents to work, they have to be left behind on the hair. That’s why oils in shampoos don’t make good conditioning agents. If the shampoo is working, any oil should be washed away.

  • OldPerry

    Professional Chemist / Formulator
    September 19, 2020 at 7:26 pm in reply to: On DEA, N-nitrosating agents and Formaldehyde releasers
  • OldPerry

    Professional Chemist / Formulator
    September 19, 2020 at 3:57 pm in reply to: Replacement of Biotin in anti-aging hydra serum

    What’s your marketing story?
    From a performance standpoint, I doubt you’ll see any difference in any of those materials.

  • OldPerry

    Professional Chemist / Formulator
    September 18, 2020 at 5:59 pm in reply to: Wanting to create a facial mask the consistency of thick honey (need help)

    @Dr_Sara - What evidence convinces you that honey is an antibiotic?

    I know that microbes don’t grow on honey but I was always under the impression that that was because of a low water activity of the substance. Is there evidence that if you put say 1 - 5% honey in a water solution that it will kill bacteria or microbes?

  • OldPerry

    Professional Chemist / Formulator
    September 18, 2020 at 2:51 pm in reply to: Alkyl Glyceryl Ether’s Performance as a Preservative?

    My opinion is that it won’t be suitable as a preservative. These ingredients are the boosters for standard preservatives.

    If they worked well enough, the industry would have switched to them long ago.

  • OldPerry

    Professional Chemist / Formulator
    September 17, 2020 at 5:39 pm in reply to: Should we increase the conditioner in this Shampoo?

    That’s one of those things you would just have to try. I doubt you need to double the amount of guar though. It works via a dilution/deposition mechanism and going from 10 to 20% surfactant shouldn’t have much effect on that.

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