Forum Replies Created

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  • Perry44

    Professional Chemist / Formulator
    February 19, 2025 at 7:13 am in reply to: Can we trust chatGPT or my questioning method is not correct?

    ChatGPT is not 100% reliable so you can’t trust it 100%. Although people are also not 100% reliable so it’s probably on par with most people you’ll ask.

    For this question, you should also ask ChatGPT to “list it’s sources” and then double check the source to see if it is accurately reporting

    Here’s what Perplexity says. It sounds more reasonable than what ChatGPT says.

    —————-

    Based on the available search results, there is no specific information about the percentage of people that can be sensitized by 3 ppm of CMI (chloromethylisothiazolinone). However, we can draw some relevant insights from the data provided:

    1. A skin sensitization study found that some leave-on products with MCI/MI (a mixture of methylchloroisothiazolinone and methylisothiazolinone) at 7.5 ppm may increase the risk of sensitization induction 3
      .
    2. Rinse-off products with 15 ppm MCI/MI were not associated with a potential increased risk of skin sensitization induction 3
      .
    3. In a Swedish baseline patch test study from 2003 to 2012, 3.1% of patients reacted to 200 ppm MCI/MI (3:1 ratio) 3
      .
    4. A more recent study using 2000 ppm patch test allergen showed an increase in positive results over time, with the highest prevalence in 2015 at 9.41% for MCI/MI 5

    Given that these studies used higher concentrations than 3 ppm, it’s likely that the percentage of people sensitized by 3 ppm CMI would be lower than the percentages reported in these studies. However, without specific data on 3 ppm CMI sensitization, it’s not possible to provide an exact percentage.

    • This reply was modified 2 days, 19 hours ago by  Perry44.
  • Perry44

    Professional Chemist / Formulator
    February 6, 2025 at 8:08 am in reply to: Some questions about my SLS powder

    Yes, it is possible. Citric acid and LABSA have different acid strengths and buffering capacities, with LABSA being a stronger acid but requiring more to achieve the same pH shift, likely due to incomplete dissociation or interaction with other components in the solution. Citric acid, a triprotic acid, offers better buffering, making it more efficient at neutralizing the alkalinity of your SLS solution.

    Your SLS powder is likely highly alkaline due to residual NaOH or Na₂CO₃ used in its synthesis.

  • Perry44

    Professional Chemist / Formulator
    February 4, 2025 at 3:16 pm in reply to: critique preservatives for my dry shampoo

    In truth, without water the sodium benzoate and potassium sorbate aren’t doing much.

  • Perry44

    Professional Chemist / Formulator
    February 4, 2025 at 1:18 pm in reply to: Guess 1% line in this Pantene shampoo

    I’d guess either before or after the Cetyl Alcohol. Probably after. I highly doubt they have fragrance at a level above 1%

  • Perry44

    Professional Chemist / Formulator
    February 4, 2025 at 1:11 pm in reply to: Facial Toner

    Your toner is solid, but honestly, toners don’t do much beyond light hydration and prepping the skin—so if you’re going to use one, here are some tweaks that might help. First, make sure the pH is between 3.5 and 4.0, or that glycolic acid won’t exfoliate properly. The formula might feel a bit sticky, so dropping glycerin to 2.5-3% and bumping up propylene glycol to 3% (or swapping in butylene glycol at 1-2%) could help. Also 0.3% Caprylyl Glycol could help boost your preservative system. These tweaks won’t turn the toner into a miracle product, but they might make it a little more aesthetically pleasing to use.

  • Perry44

    Professional Chemist / Formulator
    January 17, 2025 at 9:20 am in reply to: Analysing Unilever shampoo MSDS

    A big company like Unilever would use up to 1% silicone. I think what is listed is a blend which is only about 1/3 silicone so it seems a reasonable level.

  • Perry44

    Professional Chemist / Formulator
    December 13, 2024 at 2:13 pm in reply to: Shampoo Formulation

    Personally, I don’t like washing my hair with soap but I’m sure there might be a market for it. The major synthetic versions of detergents used in shampoos these days were invented because of the negative effects of using soap on hair.

  • Perry44

    Professional Chemist / Formulator
    December 5, 2024 at 9:31 am in reply to: Your precious share for emulsion

    Why questions are always difficult but the mostly likely reason is that you are not getting the same mixing shear and temperature profile in the large tank versus the lab beakers. The difference in energy is probably the cause.

  • Perry44

    Professional Chemist / Formulator
    December 2, 2024 at 7:26 pm in reply to: Is there a preservative in this?

    What type of product is it supposed to be, a shampoo or body wash?
    Either way, they haven’t listed a proper preservative. The only thing that would even be close is the Hydroxyacetophenone which would be a preservative “booster”. They probably just didn’t list their preservative which was incorporated into one of the surfactants.

  • Perry44

    Professional Chemist / Formulator
    November 18, 2024 at 10:19 am in reply to: Experience with fancy ingredients

    I think your approach is a scientifically grounded one although ultimately clients will likely find it unsatisfying. That might not be good for your coaching business. 😉

    You’re right there really haven’t been any innovative new materials in hair care in a long time. And scientific papers are better but in most cases, the supplier literature is all the there is. No one is spending research money to evaluate someone else’s raw material.

    But you have to also realize that this is a marketing driven industry. Marketers need stories and consumers want stories.

    My approach is to be familiar with the stories and how it can be useful for making a product stand out. But I always end with, “but of course, this isn’t really proven and probably doesn’t really work”

  • Perry44

    Professional Chemist / Formulator
    October 7, 2024 at 7:28 am in reply to: SAP with Niacinamide

    Of course there is also the question, why do you want to combine them? What do you hope to achieve by using both actives?

  • Perry44

    Professional Chemist / Formulator
    September 23, 2024 at 1:57 pm in reply to: is there anyone having experience with salicylic acid?

    It you are using it in a cleanser then it just rinses down the drain. If you’re using it in a wipe on / wipe off product, then it goes into the wash cloth. Even if some is left behind, it eventually is sloughed off the face along with all the dead skin cells that you are always losing.

  • Perry44

    Professional Chemist / Formulator
    September 13, 2024 at 11:01 am in reply to: Just checking…. Can an inorganic compound be certified organic?

    According to the USDA who would be the “organic” certifier, only things produced via agriculture can be labeled organic. Thus Zinc Oxide is not organic.

    I looked into it a little and while Salt is not organic, if you use certain additives the USDA allows you to label “made with organic ingredients.” https://www.ams.usda.gov/sites/default/files/media/7%20Salt%20and%20Preservatives%20FINAL%20RGK%20V2.pdf

    However, I didn’t find anything suggesting you could to the same with Zinc Oxide.

  • Perry44

    Professional Chemist / Formulator
    August 27, 2024 at 7:29 pm in reply to: My first diy shampoo lose viscosity after 48 hour.

    Don’t put that much glycerin in your formula. It kills your foam and can reduce the viscosity.

    The Glucoside will also kill your viscosity. You don’t need it in your formula.

  • Perry44

    Professional Chemist / Formulator
    August 27, 2024 at 6:35 pm in reply to: HELP with foundation color change

    The color instability and white patina in your W/O foundation may stem from the interaction between TRIETHOXYCAPRYLYLSILANE-coated pigments and the EASYNOV emulsifier, leading to oxidation and color shifts. To address this, consider testing different pigment coatings, adjusting the pigment-to-emulsifier ratio, and incorporating antioxidants like tocopherols to prevent oxidation. The white residue might be due to emulsifier-pigment incompatibility, so optimizing the formula with compatible fillers or co-emulsifiers could help. Additionally, ensure batch-to-batch consistency by tightly controlling raw material sourcing and manufacturing processes.

    But really, without knowing what is all in your formula it is hard to give a more specific answer.

  • Perry44

    Professional Chemist / Formulator
    February 21, 2025 at 3:58 pm in reply to: Can we trust chatGPT or my questioning method is not correct?

    ChatGPT generates responses based on the information it was trained on. Unfortunately, it can also mix up the information it was trained on and create false information. That’s why it is helpful to get sources from AIs and then double check that the sources say what the AI is claiming they say.

  • Perry44

    Professional Chemist / Formulator
    February 4, 2025 at 12:51 pm in reply to: Willow Bark vs Salicylic science

    Indeed. And raw material suppliers are not under the same advertising / marketing restrictions that you have for finished product makers. They can pretty much say whatever they want on the flimsiest of evidence. It’s up to the finished goods maker to vet the marketing material that suppliers push.

  • Perry44

    Professional Chemist / Formulator
    January 20, 2025 at 8:43 pm in reply to: Analysing Unilever shampoo MSDS

    I mean they might use as much as 1% silicone in their formula

  • Perry44

    Professional Chemist / Formulator
    December 5, 2024 at 8:56 am in reply to: Join the SCC mentor / mentee program

    Sure I can add it. Can you post a line link and a description here and I’ll update the list?

  • Perry44

    Professional Chemist / Formulator
    December 2, 2024 at 7:37 pm in reply to: Is there a preservative in this?

    That’s one of those things small start-ups do. When they get bigger and get legitimate regulatory people involved in the production and sale, they’ll start listing their preservatives (if they have any).

    This is exactly the reason I recommend to consumers that they should stick to buying products from bigger companies. They are just safer. This isn’t to say small company products are unsafe, some are and some aren’t. But for a consumer, they should err on the side of caution.

  • Perry44

    Professional Chemist / Formulator
    October 21, 2024 at 5:32 am in reply to: Is this shampoo formula real?

    There is nothing in the ingredient list that would clean hair or create foam or preserve the product so you are most likely right. They just didn’t list the ingredients that are actually making it work. They say on the label “This is not a cosmetic” so they are admitting to not following cosmetic regulations. Therefore, you can only guess what is really in the product.

  • Perry44

    Professional Chemist / Formulator
    September 16, 2024 at 6:55 pm in reply to: Just checking…. Can an inorganic compound be certified organic?

    While COSMOS and other natural standards might allow Zinc Oxide to be called “natural” no one in industry is using “natural” Zinc Oxide. All of it is synthetically produced. The stuff that is mined is broken down then chemically oxidized (French process). Actually using natural zinc oxide would expose people to dangerous levels of heavy metals.

  • Perry44

    Professional Chemist / Formulator
    September 6, 2024 at 8:45 am in reply to: SOS - Thickening Sodium Lauryl Sulfoacetate (Shampoo)

    I think it’s difficult to even get a pure “Lauric acid”. Certainly when you get lauric acid in the cosmetic industry it is still a blend of C12, C14, C10 and residual others. It’s just that it has a higher level of C12 than something like lauryl glucoside. There just isn’t any great benefit to getting 100% pure Lauric acid in our industry.

  • Perry44

    Professional Chemist / Formulator
    August 29, 2024 at 11:41 am in reply to: Update Emulsifiers and bubbles

    I think your bubble problem is more a reflection of how you are making your batches rather than the formula itself. If you are using a homogenizer on a 300g batch, I doubt your able to get the head of the homogenizer to be completely submerged. So one strategy would be to make bigger batches.

  • Perry44

    Professional Chemist / Formulator
    August 28, 2024 at 9:54 am in reply to: Update Emulsifiers and bubbles

    You haven’t asked a question. You simply put “update” then gave some pictures and description.

    If you want some assistance please summarize what the problem is and what further questions you want answered.

    Honestly, there are dozens of discussions going on here. If you want a response you have to make it EASY to answer. You can’t expect people to go back and review the entire previous thread to figure out what you want to know now.

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