Microformulation
Forum Replies Created
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I have heard it is even found in cancer cells!
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Water
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I used it recently in a Sugar Scrub. I was so glad I had a Silverson otherwise it would have taken forever.
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At a Contract Manufacturer I once worked at we did a surfactant system thickened by fumed silica. Best advice is to have a good homogenizer.
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@avick In the US to make the claim you are limited to the actives and concentrations as outlined in FDA monograph.
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Unfortunately with TTO you can’t make a claim that it treats Tinea pedis.
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@The_Microbiologist Microbiology and Process sanitation is a huge part and often overlooked. It may not be Chemistry but is arguably a topic for Cosmetic Chemistry.
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I agree with everyone. I would try to avoid an in-depth Chemistry instruction as it would take too much time. I would cover basics of solutions and emulsion technology.
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Wow, what kind of packaging would you need to use with those golf ball size exfolliant beads????
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I think God has the trademark on Mango. Might want to take that up with Him. Seriously too many sources to count offer the Mango Butter, Mango Oil and the Extract.
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The inci is probably truncated. It could be the oil or the butter or even the fruit extract.
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That is really a broad subject and probably more than anyone would be able to do in this Forum. In general most ointments are occlusive products traditionally based upon Petrolatum in many cases. Generally you are looking at a W/O emulsion. Further complicating the fact would be that Athletes Foot products are generally Over-The-Counter (OTC) products.
I would suggest googling some sample Formulations first.
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It is an important issue. I have mentored many small crafters working in their kitchen. A big issue is aeration. I urge them to at least invest in an entry level variable speed mixer. They can start at $150 or so on Ebay.
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For the amount of money that one would spend on a high end stick blender they could be transferring overr to lab type blenders. Variable speed and a mixer stand are big pluses/ I have several Formulations which require slow mixing during the cool down (from 75C to <40C). This process can take upwards of 30 minutes plus. Try holding that stick blender that long and try getting the proper mix speed with a stick blender.
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@Perry You have an RSS Feed for the Chemist Corner blog since I get it emailed to me that way.
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They beat me to it, but your pH is pretty high. That needs to be addressed and could be a quick fix.
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Chelator is the first thing I would try. Also, what is the final pH?
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Welcome Mike! Pretty varied experience!
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@Bobzchemist Interesting perspective but you are right that it would be difficult to perform these studies under a deadline. In my practice I have more leeway to do so but I can remember my days in Contract Manufacturing. I would have had to barricade myself into the lab to get that much time.
I do see the resistance to do knock-off experiments especially in Chemists newer to the Field. They believe that they can design a Formulation on paper and it will perform flawlessly. I think it is crucial for them in regards to career development to see how these Formulas don’t always equate to real world experience. I have learned as much from my unsuccessful bench jobs as I have learned from my successful ones.
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I order it from Dr. Brown whenever he restocks his Plutonium for the Delorean.
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Everything I make is Natural. I only use the first 92 naturally appearing elements in the Periodic table.
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Cognis has a whole line of Green Ecocert emollients in their Cetiol series and they work well.
Lastly, what Natural standard are you following? I am never impressed with undefined “Natural.” Following a credible standard is tantamount.
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Moringa Oil is also a replacement.
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@gustavo Glad to see another Pharmacist in here. I have heard great things about Brazils Cosmetic Industry.
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http://www.cosmeticsandtoiletries.com/formulating/function/preservatives/102957044.html?mobi=y
http://www.personalcaremagazine.com/Print.aspx?Story=4108
Chelating agents are able to enhance
the efficacy of most preservatives. This occurs as the chelator removes
metal ions from cell walls of the microbes. The weakened walls then
allow the biocide to penetrate and destroy the microorganisms. Although
the boosting effect of chelating agents on preservatives is well known,
the environmental fate of these materials has been debated. To avoid the
environmental discussion about chelating agents, readily biodegradable
alternatives have been introduced to the market.I use a chelator with PE9010 each time to boost its efficacy. This need was passed onto me several years ago by Wolfgang Siegert at Schulke. It can be challenging as EDTA is a big no no in most “Natural” standards (NPA, NSG, WF’s). In that case I will generally use Dermofeel PA-3 from Dr. Straetmans (Kinetik in the US).