[Marko]

Quality of materials. For all materials I have certificate with MB tests, some of them PhEUR quality, regarding dishes, before usage I apply cleaning procedures that I saw in while working in the pharma industry (water, diluted ethanol).

Regarding package, i was thinking to replace spray mist cap with lotion pump, not just because possible contamination through inhalation, but also because I have a problem to find decent quality spray mist cap (clogging from time to time, spraying problems..).

Exposure to essential oils can be calculated from % of every oil component in lotion, and with the volume that is applied if it is used according to label.

I was considering to adding small amounts of xanthan gum and/or cetyl alcohol to stabilise emulsion. What is your experience with these ingredients?
Do you think that lotion shelf life would be longer if I succeed to prevent phase separation during shelf life?

[Marko]

I agree that amber glass does not prevent completely evaporation, but for products which have essential oils in some % it is, in my opinion, much better option than plastic container (permeability, interactions…). Also, many manufacturers use glass as primary package material for pure essential oils.

pH of lotion is 4,75.

I now that parabens or phenoxyethanol is good solution for preservation but I was looking forward to use some COSMOS approved preservatives, because in pharmacy I see every day that pressures from market leaders regarding “paraben free, phenoxyethanol free, etc” cometic is rising.

You think 1% Geoguard 221 in this formula is not enough for 2 years shelf life?

In your opinion Geoguard 221 would not be inactivated in presence on nonionic surfactant?

Thanks for advice about spray mist cap!

[Marko]

Here there are some studies:

https://pubmed.ncbi.nlm.nih.gov/9828867/

https://pubmed.ncbi.nlm.nih.gov/12451368/

https://pubmed.ncbi.nlm.nih.gov/25842469/

https://pubmed.ncbi.nlm.nih.gov/27123160/

https://pubmed.ncbi.nlm.nih.gov/29159502/

[Marko]

Amber glass bottle GL18, with plastic mist sprayer cap.

I am aware od evaporation od essential oils, so my choice was amber glass.

[Marko]

It is for commercial use and in my country (B&H, Europe) it can be advertised “helps prevent hair loss” or “helps reduces dandruff” but I can not have medical claim on label for this kind of cosmetic product.

As I pharmacist I can tell you there is many studies that supports usage of these essential oil in fighting hair loss and dandruff.