Kull_Axel
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I think CBD helps people to cure anxiety and insomnia. I have seen a lot of people that say it changed their life so I started to investigate. Here you can find some info regarding the anxiety experiment with cbd https://www.ncbi.nlm.nih.gov/pubmed/21307846
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Perry said:@Kull_Axel - My starting opinion about any ingredient is that it has no noticeable effect. I would easily change my mind when shown scientific evidence. But I’m not impressed by anecdotal stories and marketing materials from ingredient suppliers.
What specific benefits do you believe you get from topical application of CBD? What evidence convinces you that these benefits are real?
I’m certainly willing to change my mind if the evidence warrants it.
Do you think CBD doesn’t have any benefits in general or when used in creams and lotions?
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globalwidget said:After working with several different CBD isolates, I can say that yes they can be different. Depending on where you are getting it from, how it was refined, what solvents were used in the extraction process, and other factors, can make the isolates easier or more difficult to work with. Like @Perry said, their is no standard. You’ll definitely want to look at C of A’s to find the most pure isolate you can. There is no such thing as a broad spectrum isolate, an isolate by definition should have minimal to zero other cannabinoids in it.
Thank you for the information, but what you mean by “C of A’s ” sorry but i’m a noob in chemistry.
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Perry said:@Kull_Axel - If you were just buying CAS 13956-29-1 then the price should be pretty consistent. However, it’s unlikely that you are comparing the same ingredient. The ingredient from Sigma Aldrich is sold as a 1mg/mL sample in methanol. That’s the cannabidiol molecule. I’m sure there are other samples that are an extract from a plant diluted but they just call it cannabidiol because there is no standard.
But I agree with @@Belassi - whether you get an expensive, pure sample or some cheap diluted extract won’t matter much because you won’t be able to tell any performance difference anyway.
Why you think there is no performance difference?
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Belassi said:Well not really. The molecules might be identical, but one might have been grown on the side of a highway, in a hydrocarbon exhaust breeze, and the other… no it’s all nonsense! It doesn’t work anyway, not topically. I grew some 17% plants and made a 10% cream (obviously it would have cost a fortune) and it was useless.So for you CBD didn’t work at all? Did you just try the cream?
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Microformulation said:Also, why sulfate-free? If you do some market research into the mainstream shampoos, sulfates dominate in this market. Sulfates get a bad rap and they are safe and non-irritating when properly formulated. Since it isn’t for marketing, it doesn’t have to hit the market and overcome some preconceived marketing fallacy.
I’m looking for something without sulfate because the veterinary suggested me to buy something without sulfate since my dog skin it’s delicate. Maybe he was affected by marketing fallacy too, I don’t know. By the way, thanks for the formulas guys. I will study it and see if I can make a small amount as a test. May I also ask what do you think about this product CalBlend® PC (Sodium C14-16 Olefin Sulfonate, Cocamidopropyl Betaine, and Cocamide MIPA) there are any advantages using this one instead of the Decyl Glucoside?
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Microformulation said:Not to beat a dead horse, but this is why I dislike the term “natural.” It means nothing. Usually, it is a barrier since it restricts the Formulation. However, there are cases on the other end of the spectrum. From a purely objective standpoint and referencing the natural standards, this would not be demonstrably “natural.” Now, that would not be an issue with most shampoos in this market sector. The price points which products have to meet in these products is very tight. In almost every case there is huge pressure to stay within the market prices. If you look and get objective sales data (not cool website, they must be huge), you will see that very few “natural” lines have prospered in this sector.
Thank you for the information. I’m actually looking for personal use. I don’t want to pay 30$ for “natural” dog shampoo. That’s why I’m here, trying to understand the basics. Like I said before I’m not a chemist, but I’m just fascinated by the chemistry world.