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Sodium benzoate is generally considered compatible with a wide range of ingredients. However, there are some conditions and combinations that may lead to undesired effects. Here are a few factors to consider:

1. Vitamin C (Ascorbic Acid): The combination of suika game sodium benzoate with ascorbic acid (vitamin C) in the presence of heat or light may result in the formation of benzene, a potential carcinogen. This reaction is more likely to occur in acidic conditions.

2. Certain Artificial Colors: Some artificial colors may react with sodium benzoate under specific conditions, potentially leading to changes in color or taste. It’s essential to check for compatibility based on the specific formulation.

3. Certain Metal Ions: In the presence of certain metal ions, such as copper or iron, sodium benzoate may undergo reactions that could affect the stability and safety of the product. Proper formulation and testing are crucial to ensure compatibility.

4. High Heat: Exposing sodium benzoate-containing products to high temperatures for prolonged periods may compromise its effectiveness as a preservative.

It’s important for food and beverage manufacturers to conduct compatibility testing and consider the specific conditions under which their products will be stored and consumed. Additionally, consulting regulatory guidelines and seeking expert advice can help ensure the safe and effective use of sodium benzoate in various formulations.