Adamnfineman
Forum Replies Created
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Adamnfineman
MemberNovember 22, 2024 at 10:02 am in reply to: Liquid gums / liquid substances to gelify waterI think you’re looking for pre-dispersed polymers/thickeners such as:
Aculyn 22 (Acrylates/Steareth-20 Methacrylate Copolymer)
Crothix Liquid (PEG-150 Pentaerythrityl Tetrastearate (and) Aqua (and) PEG-6 Caprylic/Capric Glycerides)
Carbopol Aqua SF-1 Polymer (Acrylates Copolymer)Look at the literature for each as the Aculyn and Carbopol need to be neutralized to get your viscosity. You might have to add a bit more than 0.5-1.0%.
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It doesn’t seem like you listened to any of us when you posted this same thing last time. How would you like us to help you when you don’t help us?
chemistscorner.com
What is wrong with this formulation?Nitrosol EDTA carbomer white oil sunflower seed oil IPM shea butter Cetyl Alcohol Stearic Acid Emulsion wax Silicone Oil Dimethicone…
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It seems this post was made at the same time as the one I linked and isn’t a copy of the last post, my apologies.
We still need the information requested to be of any help.
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Could you share your formula or at minimum the list of ingredients? Expansion can be a preservation issue.
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Glad you could confirm you do indeed have skatole.
I’m even more curious about the application now. Is it one of those bathroom sprays meant to eliminate malodors if you spray it in the bowl before doing your business?
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I don’t have an answer to your question, but I do have a question of my own. What is your intended application? Fragrance?
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Based on the ingredients listed and the amount of information we have, I’d say the issue is a lack of water.
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Use as little biotin as you possibly can, then filter your bulk before filling.
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Hello,
I’m part of the R&D team at a contract manufacturing company based in South Florida. My colleague is working on recreating this product right now. He’s been successful in the lab and is trying to find equipment to scale up his process as we speak. If you’d like to set up a meeting to discuss specifics, feel free to send me a private message. -
In manufacturing, a batch needs to have its pH raised or lowered to meet specifications. Usually, the pH adjuster is included in the formula and we simply have to add a bit more at the end. However, it does happen that a formula doesn’t have one or it contains an acid but when we measure pH it comes out too low and we need to add an alkaline pH adjuster. We often use sodium hydroxide for this as it’s cheap and we have a lot of it on hand. This would be classified as an incidental ingredient and does not need to be disclosed on the label. So there is a good chance that other products you use also contain sodium hydroxide but don’t include it on the label.
When you say salt water do you mean specifically sodium chloride? That may happen if there are other ionic ingredients in the formula that release a chloride ion when dissociating. Depending on the formula, there could many different sodium salts “formed” but the concentration would be incredibly low. I put that in parentheses because most sodium salts are soluble in water so the sodium would remain as a free floating ion unless all the water is removed.
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To answer your question, I find it highly doubtful that there could be undissolved sodium hydroxide remaining in a product. Sodium hydroxide is not added as a solid. Generally, it is dissolved in water before being added to the product to ensure it disperses quickly and allow the compounders greater precision when weighing it.
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There are many other choices. @PhilGeis has listed some of them above. Do you have any other constraints when it comes to preservatives?
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Adamnfineman
MemberMay 10, 2024 at 10:22 am in reply to: Sedimentation problem (Problème de décantation)Bonjour!
Peux-tu partager ta formule complète? Si non, peux-tu partager les autres ingrédients que t’utilize? Include les spécification de pH et viscosité stp.
Ma première supposition est que tu n’as pas assez de viscosité pour suspendre ton opacifiant. Ma deuxième supposition est que ta formule a des électrolytes qui interfèrent avec la stabilité de votre opacifiant.
English:
Hello!
Could you share your complete formula? If not, could you list the other ingredients used? Include the pH and viscosity please.
My first guess is that you don’t have enough viscosity to suspend your opacifier. My second guess would be that your formula has electrolytes which interfere with your opacifier’s stability.
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Hello,
Is that 0.1% EDTA the active matter added or the amount of solution added? If it’s the latter, I would increase it to have at least 0.1% active. Also, someone correct me if I’m wrong but I don’t think EHG and EDTA are enough on their own to form a robust preservative system.
When adding up the % I got 92%. Depending on what they are, 8% of additives could greatly affect your viscosity and clarity.
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I second this query. There are some interesting, borderline OTC, claims that I would love for the FDA to take a look at.
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Hi @Nils,
I work at a contract manufacturing company that has developed and produced OTCs for the US, EU, and Asia. We are based in the US and work out of an OTC approved facility following GMP guidelines. I’d love to get you in a meeting with our R&D department to discuss your product and goals.
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Adamnfineman
MemberNovember 18, 2024 at 10:35 am in reply to: Preservation Need for High Glycol Product?Weird, I added the whole brochure and only the first page is showing. In case it happens again, the INCI is [Glucosamine HCl (and) PCA (and) Glutamine (and)
Lysine HCl (and) Betaine (and) Yeast Beta Glucan]EDIT: It seems you have to download the file to see the rest of the brochure.
- This reply was modified 2 weeks, 2 days ago by Adamnfineman.
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Adamnfineman
MemberNovember 11, 2024 at 9:38 am in reply to: Preservation Need for High Glycol Product?Would this material happen to be ScentARC?
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It can be dispersed in polyols such as propylene/hexylene glycol, propanediol, or a blend of these and glycerin.
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Replace all instances of cationic here with anionic. I replied a bit too early for my brain to be working properly.
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What I’m saying is there are no byproducts unless all the water is removed or there is a molecule that makes an insoluble salt with sodium. The latter is very unlikely because sodium salts are soluble in water with exceptions that wouldn’t generally be seen in cosmetics such as sodium bismuthate. All that will happen is the sodium will hover near cationic molecules or water. If the water is removed, the sodium will then form salts with the cationic molecules it is most attracted to.
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Adamnfineman
MemberMay 14, 2024 at 7:46 am in reply to: Sedimentation problem (Problème de décantation) -
I can’t say definitively whether that would be enough because I haven’t tried and tested that combination. Maybe @PhilGeis can shed some more light on this.
I don’t know whether it’s too much as I don’t know what it is exactly. I do know that (most) extracts and peptides have little to no effect in leave-on products and even less in a rinse-off products like shampoos. What exactly are your additives? Are they being added for claims or efficacy? If efficacy, what do you expect them to do?
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I would recommend adding a preservative such as phenoxyethanol in a 1:9 EHG:PE ratio. We generally use 1% of this ratio along with 0.1% EDTA for our hair care products without issue. It’s sold as a blend by suppliers, my go to is Euxyl PE 9010.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082626/
I do find it weird that you’re omitting 8% of the formula. Especially when based on your other comment part of that includes salicylic acid, which is notoriously finnicky.
ncbi.nlm.nih.gov
Ethylhexylglycerin Impairs Membrane Integrity and Enhances the Lethal Effect of Phenoxyethanol
Preservatives are added to cosmetics to protect the consumers from infections and prevent product spoilage. The concentration of preservatives should be kept as low as possible and this can be achieved by adding potentiating agents. The aim of the study … Continue reading
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I think they’re referring to adding the xanthan gum slurry (assuming you’re mixing it with the glycerin) after your emulsion has been made.
Also, did you mean dimethicone? Or are you adding herbicide to your moisturizer?