Home Cosmetic Science Talk Formulating Triethanolamine and nitrosamines Reply To: Triethanolamine and nitrosamines

  • MarkBroussard

    Professional Chemist / Formulator
    December 2, 2014 at 1:34 pm

    @lewhitak:

    I generally use the following preservation system:
    (1)  Gluconolactone/Sodium Benzoate (1.25%)
    (2)  Trisodium Ethylenediamine Disuccinate (0.3%)(chelating agent) + Citric Acid (0.2%)(Preservative Booster)
    (3)  1,3-Propanediol 3.0% (Preservative Booster)
    Add all of the above to your water phase right up front under high shear, then heat to 77C and hold for 20 minutes.  That generally ensures the Gluconolactone/sodium benzoate stays in solution. 
    Based on some research that I came across recently, I am going to swap the Trisodium Ethylene … and replace it with Dissolvine GL-47-S (Tetrasodium Glutamate Diacetate) … the studies showed a significant enhancement in preservative efficacy using Dissolvine + Citric Acid.

    Also, Zemea has a nice study showing enhancement of Gluconolactone/Sodium Benzoate with 2% to 6% 1,3-Propanediol.

    If I’m making a cream, lotion, etc. where crystal clear is not an objective, I also add in Caprylyl Glycol/EHG.

    Hope that helps.