Will this work?? - Chemists Corner

Tagged: formula help, manufacturing, preservatives

Formulating

Will this work??

Posted by Jake99 on January 23, 2019 at 5:04 am

I am thinking of making a cosmetic cream,and as i dont have all the ingredients,i cannot experiment.please feel free to suggest other quantity,even remove for the ingredients.here it goes

1. 70-?%petrolatum
2. 18 %water
3. 1% hydroquinone
4. 0.025% tretinoin
5. 1% clindamycin phosphate
6. 4% nicotinamide

what emulsifier will be good?
What preservative if serve best?
Will they react?
Will it work on clearing acne???
Thank you
Im a newbie

Jake99 replied 5 years, 10 months ago 5 Members · 10 Replies
10 Replies

ngarayeva001

Member
January 23, 2019 at 11:08 am

If your goal
is to make your face falling off then it will work. Are you making a nuclear
bomb or what? Your formula isn’t equal 100% and you are trying to make a
concoction with 3% of hydroquinone and tretinoin (how much?). These are not
toys. Learn how to make simple o/w lotions first then move to actives. I am not
even sure you can buy tretinoin and hydroquinone.
Chemist77

Member
January 23, 2019 at 1:44 pm

@ngarayeva001 those are the serial numbers, but still agree that not for newbie.
Jake99

Member
January 23, 2019 at 3:32 pm

Ok..thank you both?
ngarayeva001

Member
January 23, 2019 at 3:45 pm

Sorry it showed as 3.1% on my phone. But I think any amount of hydroquinone is not safe for a beginner. Start from simple products and then move to actives.
Jake99

Member
January 23, 2019 at 3:52 pm

yes sir
Sibech

Member
January 23, 2019 at 4:18 pm

@Jake99 Definitely start with a regular lotion as @ngarayeva001 suggested.

You are missing an emulsifier to keep the water and petrolatum together. As you are starting out as a newbie try something along the lines of simple formulas from lotioncrafter.com or makingcosmetics.com

You should also be aware for the future that Clindamycin is not a cosmetic ingredient. It is a drug (antibiotic) which could lead to the development of MRSA strains if misused.

Tretinoin is likewise a drug compound, OTC in the US. The compound is prone to oxidation and requires a decent amount of experience to formulate a stable and safe product.

You can read a lot on hydroquinone on the forum, but I would suggest steering clear of it altogether.
Jake99

Member
January 23, 2019 at 4:35 pm

Thank you.I’ll do as you recommended?
I thought mixing hydroquinone with clindamycin would be like a two in one product.will they react though?just curious..thanks
Doreen

Member
January 23, 2019 at 4:39 pm

@Jake99
I don’t know the regulations in the country where you live, but I don’t think you can buy clindamycine either (same with tretinoin as mentioned by ngarayeva001), they’re not cosmetics.

Edit: I see Sibech has answered this in the mean time.
Sibech

Member
January 23, 2019 at 5:08 pm

@Jake99 No Chemically clindamycin is not likely to react with hydroquinone as is.
Jake99

Member
January 23, 2019 at 6:07 pm

Thank you