Home Cosmetic Science Talk Formulating What ingredients are incompatible with sodium benzoate?

  • What ingredients are incompatible with sodium benzoate?

    Posted by Bluebird on January 14, 2024 at 5:11 am

    I read a blog post here (“The best cosmetic preservatives”)by @sromanowski.

    It said organic acids and their salts, including sodium benzoate, may have a formulation incompatibility issue with “cationics, some proteins, nonionics.”

    What are “cationics”? In cosmetics lingo, does cationics mean cationic surfactants only, or just in general, anything cationic?

    For instance, if you mix sodium benzoate at a low pH with lysine, a positively charged amino acid, do you expect some kind of precipitation or non-covalent but ionic interactions that are expected to have practical meaning of any kind?

    Is mixing cationic proteins in low pH with sodium benzoate expected to have benzoic acid interacting with said proteins, is that why it may be incompatible with “some proteins”?

    If there are known examples of ingredients you know that are incompatible, I’d love to know to get a better sense.

    oilumiun12 replied 8 months ago 8 Members · 7 Replies
  • 7 Replies
  • paulryan

    Member
    January 15, 2024 at 4:49 pm

    Sodium benzoate is a commonly used preservative in the food and beverage industry, and it is generally considered safe for consumption when used within regulatory limits. However, certain conditions and ingredients can lead to incompatibility or the formation of benzene, a potential carcinogen, when sodium benzoate is present. If you have specific concerns about the compatibility of sodium benzoate with certain ingredients in a product, it is advisable to consult with food scientists, regulatory experts, or professionals in the field of food chemistry. Source: https://chinnurology.com/

  • brownsunny148

    Member
    January 15, 2024 at 9:04 pm

    Sodium benzoate is generally considered compatible with a wide range of ingredients. However, there are some conditions and combinations that may lead to undesired effects. Here are a few factors to consider:

    1. Vitamin C (Ascorbic Acid): The combination of suika game sodium benzoate with ascorbic acid (vitamin C) in the presence of heat or light may result in the formation of benzene, a potential carcinogen. This reaction is more likely to occur in acidic conditions.

    2. Certain Artificial Colors: Some artificial colors may react with sodium benzoate under specific conditions, potentially leading to changes in color or taste. It’s essential to check for compatibility based on the specific formulation.

    3. Certain Metal Ions: In the presence of certain metal ions, such as copper or iron, sodium benzoate may undergo reactions that could affect the stability and safety of the product. Proper formulation and testing are crucial to ensure compatibility.

    4. High Heat: Exposing sodium benzoate-containing products to high temperatures for prolonged periods may compromise its effectiveness as a preservative.

    It’s important for food and beverage manufacturers to conduct compatibility testing and consider the specific conditions under which their products will be stored and consumed. Additionally, consulting regulatory guidelines and seeking expert advice can help ensure the safe and effective use of sodium benzoate in various formulations.

  • ketchito

    Member
    January 16, 2024 at 7:29 am

    Just as a comment, the reaction of ascorbic acid with sodium benzoate requires very specific conditions, not usually met in cosmetics.

    Now, I wouldn’t worry much about mixing Sodium benzoate with cationic surfactants at low pH, since you’ll have benzoic acid instead (the extra hydrogen will “hide” oxygen negative charge you have in benzoate, preventing it to react with cationics). The story would be different at higher pH, but cationic systems in cosmetics are usually use in rather acidic bases.

    • PhilGeis

      Member
      January 30, 2024 at 9:37 am

      Agree, the ascorbic acid reaction to benzene is not a concern in this context. Might have problems with some clays, but I’d not worry much.

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  • oilumiun12

    Member
    March 18, 2024 at 9:44 pm

    At pH between 2.5-4.0 sodium benzoate is most effective to inhibit the growth of most bacteria. Sodium Benzoate is the inactive salt of benzoic acid. It is soluble in water where it converts to benzoic acid, its active form, at a low pH(<4.0).

     

     

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