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  • Toothpaste suggestion

    Posted by Fekher on December 19, 2024 at 12:32 am

    I’am thinking to make basic tooth paste gel with :

    Glycerin and sorbitol : 35-60%

    Water: qsp

    CAPB and coco glucoside : 2% active surfactant

    Hpmc:1-2%

    Preservtive : may parabens as needed

    Menthol: 0.1%-0.3%.

    Sodium sacharin: 0% to needed level

    Peg 40 castor oil: 1-4%

    Triclosan : if it has really benifet at adequate level

    Essential oil : may added if needed

    Sodium bicarbonate : as needed

    So I want to know :

    1)without powder as carbonate calcium… Can toothpaste gel works well?

    2)What is the best thickener for tooth paste:sodium cmc almost used, Hec, Hpmc ?

    3)Is my surfactant system fine for sush product and why they use sls and they don’t use sles? I feel from researching that used surfactants in toothpaste are limited is true and according to what the limitation especially sls is allowed ?

    4)What is the best pH for tooth paste? many insist that acidic pH is bad however is not slightly acidic (maybe 4 to 4.5) is more efficient to remove limestone?

    5) for product contains 60% glycerin or more is preservative needed? What preservative can be used in sush product other then parabens and sodium benzoate?

    6) What about the effeciency of triclosan and sodium carbonate as actives and any better replacement for fluoride?

    • This discussion was modified 1 month ago by  Fekher.
    Herbnerd replied 1 week, 4 days ago 4 Members · 6 Replies
  • 6 Replies
  • ketchito

    Member
    December 19, 2024 at 7:08 am

    Just as a note, fluoride reinforces teeth enamel to reduce abrasion, so none of those replacements are such thing.

    Also, CAPB is a por foamer on its own; glucosides are better, but not at the level of sodium lauryl sulfate which is often used. Also, at that level of surfactan and with very large amounts of polyols, I don’t think your product would be a good cleanser. Check patents of big companies as reference.

  • Aniela

    Member
    December 19, 2024 at 7:22 am

    Hi,

    Although old, this article will answer some of your questions https://pmc.ncbi.nlm.nih.gov/articles/PMC7245492/

    • Fekher

      Member
      December 22, 2024 at 9:55 am

      Thanks

  • Herbnerd

    Member
    December 19, 2024 at 1:27 pm

    As a formulator of toothpaste (I tend to work to Natrue standards, so some of the ingredients you’ve listed are not permitted under this standard, and as such, I have little experience of them).

    First thing I notice - no abrasives. You mentioned calcium carbonate and sodium bicarbonate “as needed”. I’m unsure whether you mean this to be used as an abrasive or whether you are thinking to manage pH. - but unsure if you mean these to be abrasives. You could consider, silicon dioxide (there are gel grades and abrasive grades).

    “Glycerol/Sorbitol” - 35-60%. 35-40% is more around the level you want. Too high, you end up with a paste that looks more plasticy. I have one formula with the glycerol around 20% - it produces a dull looking flat paste, that solidifies rather quickly in air - and I would reduce this, but because the glycerol/Xylitol/Steviol glycosides produced a sweetness almost comparable with saccharine - I am stuck with it)

    CAPB/Coco Glucoside - Levels look about right but you will need to experiment to see how it affects the flavour of your toothastes.

    Preservatives - We don’t use any. We have tested to BP standards, cosmetic microbiology standards, USP standards. As well as testing water activity. We have done ambient and accelerated stability, and tested it every way we can. We have proven we don’t need it. However, if you are not prepared to test to the levels we have, use preservatives - and parabens are the best in toothpaste. There are other options available - but potassium sorbate will not work at all with a calcium carbonate or sodium bicarbonate paste (pH is 8-8.5), and very limited use in a silicon dioxide gel - because you will need to lower pH further and this is not great for teeth.

    Triclosan - I don’t use it. It also seems to be restricted in the markets we generally sell in.

    To answer your specific questions.

    Yes, you can have a toothpaste without calcium carbonate in it - but consider the options you do want to use as an abrasive. Silicon dioxide abrasives such as Evonik Zeodent grades have targeted RDA/PCR at a particular usage rate. Bicarb abrasiveness depends on particle size. There are others you can use.

    Thickener - I would use Sodium carboxymethylcellulose (Cellulose gum) every time. But that is a personal preference based on experience

    Surfactants - most use SLS because it is the easiest to work with and has fewer off flavours to work with. I use Lauryl glucoside and sodium cocoyl glutamate. Seems our marketing team and customers expect product to be free from SLS. The ones I use do impart some off flavours that are hard to mask.

    pH range - I wouldn’t go below pH 5.5. This was recommended to us by the good chaps at OHRI at Indiana Uni.

    Fluoride - there is no replacement for fluoride. The trend is towards using nano-hydroxyapatite, but fluoride really does bind to teh calcium in teeth and strengthen them. If you use fluoride, avoid using it in a calcium carbonate toothpaste. The total fluoride will remain at the levels on input, but the free-fluoride will drop and sodium fluoride or sodium monofluorophosphate will react over time reducing your free-fluoride (which does nothing to help teeth). Triclosan will not replace fluoride.

    • This reply was modified 1 month ago by  Herbnerd.
    • Fekher

      Member
      December 22, 2024 at 9:09 am

      @Herbnerd thanks a lot for you interesting share, I want to know why your preference is sodium cmc and according to what you chose sush surfactants?

      • Herbnerd

        Member
        January 7, 2025 at 9:41 am

        CMC just produces a more stable gel that works in many manufacturing methods. Xanthan just doesn’t have the same sort of gel strength.

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