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Surgical Handwash
Hello everyone.
I have a question regarding the content of Chlorhexidine Gluconate in surgical handwashes. Majority of the surgical handwashes mention that they contain 4%w/v Chlorhexidine Gluconate. Is it an active concentration of 4%w/v or is it 4%w/v of Chlorhexidine Gluconate 20% solution which is the most commonly used form of Chlorhexidine Gluconate ?
If the former is true then the requirement would be 20% w/v of Chlorhexidine Gluconate 20% Solution in order to achieve an active concentration of 4% w/v.
Awaiting your wise response.
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4 Replies
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This forum is more connected to cosmetic chemists. Can you please advise of any suitable forum related to microbiology and pharmacology where my query can have reasonable response ???
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You might check for groups on LinkedIn.
Or if there is a professional society for Microbiology or Pharmacology you can see if they have a forum.
In truth, a forum like this is an anomaly. There aren’t a lot of industry specific forums because the people with the expertise work for companies and are often not allowed to share information.
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Chlorhexidine Gluconate 20% Solution %v/v to get Chlorhexidine %w/v.
2% CHG in70% alcohol preparation in total volume 1,000 mL
20% chlorhexidine gluconate 100 mL
95% ethyl alcohol 740 mL
sterile distilled water to 1,000It’s been a long time i might forget smth. pls check with your supplier or FDA again.
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Check formula or your label claim.Chlorhexidine Gluconate solution 4% orChlorhexidine gluconate 4%.If claim chlorhexidine Gluconate 4% than you required 5x chlorhexidine gluconate solution.
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