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Stabilizing Hydroquinone, arbutin, Resorcinol and Retinol based creams from oxidation and browning
I am having a lot of difficulty in maintaining stability and shelf life of creams containing the following ingredients. I prepared 3 lotion prototypes with 2% HQ, 0.5% Retinol and 4% Arbutin, 0.3% Phenyl ethyl resorcinol with standard emulsifiers in lecithin base.The formula oxidized fast and turns brown by 3 months when kept at Room Temperature. Encapsulating these actives in lecithin system and adding antioxidants VitC and E improved stability by 5 more months. I would like to know if its possible to maintain shelf life upto a year.
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6 Replies
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a) What packaging? You DID use airless packaging I hope?
b) What antioxidants did you use. I don’t regard vitamin C as an antioxidant! It oxidises readily. -
instead of vitamin C and E, try adding sodium sulphite and BHT
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Thanks. I used tetrahexyldecyl ascorbate (VitC), and tocopherol. For packaging i used amber colored bottle for all.
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Yes i used opaque airliess pumps (1-2 oz) bottles.
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what level of sodium sulphite and BHT do you recommend?
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I suggest adding 0.7% pine bark extract. (pycnogenol)
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