Home Cosmetic Science Talk Formulating Stabilizing benzoyl peroxide? Increasing viscosity? Antioxidants?

  • Stabilizing benzoyl peroxide? Increasing viscosity? Antioxidants?

    Posted by Zink on October 4, 2022 at 6:54 pm

    Have a formula I’d like to extend the shelf-life of to make it more viable, in other words extend the time it takes for its BP content to degrade 10% below the label value of 3%. Ideally you want this to be beyond 12 months.

    The base formula has 10% alcohol, 5% DMI, Curoxyl and a gellant. It holds together well, but shelf-life could be better.

    Just making it thicker? Any other ideas?

    Pharma replied 1 year, 11 months ago 3 Members · 6 Replies
  • 6 Replies
  • Pharma

    Member
    October 5, 2022 at 4:43 am

    Chelates can help (depending on purity of your ingredients).

  • ketchito

    Member
    October 5, 2022 at 12:00 pm

    I agree with @Pharma. You can also try increasing pH of your product, add an antioxidant and -as you mentioned-, increase viscosity of your product.

  • Zink

    Member
    October 5, 2022 at 2:23 pm

    Thanks! Any specific chelates that could work here? Optimal pH? 

    Think it needs a multi prong strategy.

  • Pharma

    Member
    October 6, 2022 at 4:43 am
    I would use phytate because it’s the one which comes to my mind with the best oxidative stability. Maybe there are other untypical products which might increase BP stability?
    @ketchito‘s advice to use an antioxidant in an oxidant formulation… maybe not the best idea… ;)
  • ketchito

    Member
    October 6, 2022 at 11:53 am

    @Pharma In the past, I’ve worked on a stain remover based on hydrogen peroxide. To stabilized (because the product became unstable over time, making bottles to swell), we used a close relative of BHT and it worked. I believe it worked preventing (or scavenging) free radicals. Might this be applied in the case of this BP product? 

  • Pharma

    Member
    October 6, 2022 at 6:46 pm

    @ketchito I stay correted. I completely ignored BHT and related radical scavengers but was mentally locked in ‘traditional’ antioxidants. Because BHT is a sterically hindered ‘monophenol’, it is quite oxidation stable though I assumed even those phenolics couldn’t take such an oxidative environmentand. But yes, capturing radicals should indirectly render peroxides more stable. I just couldn’t come up with anything stable enough…

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