Home Cosmetic Science Talk Formulating Stability of CMI MI & formalin at pH 10 for ~30 minutes

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  • Stability of CMI MI & formalin at pH 10 for ~30 minutes

    Posted by Abdullah on June 5, 2024 at 7:21 am

    If we increase pH of a surfactant solution preserved with 0.03% CMI MI+ 0.03% formalin to pH 10-11 for ~30 minutes, then adjusted to pH 6. Will it decrease the quality and stability of CMI MI & formalin?

    If yes, then by what percentage?

    Abdullah replied 5 months, 1 week ago 2 Members · 4 Replies
  • 4 Replies
  • PhilGeis

    Member
    June 5, 2024 at 8:05 am

    Doubt it’s stable. CMIT in any simple aqueous solution is unstable and alkaline pH is tough on it as well.

    • Abdullah

      Member
      June 5, 2024 at 11:30 pm

      It is a surfactant solution.

      What about formalin at that high pH for ~30 minutes?

      • PhilGeis

        Member
        June 6, 2024 at 5:56 am

        I don’t have much good information to share on that. I do understand formaldehyde is more reactive at alkaline pH. In another context I’ve used formaldehyde @pH as preservative 10 for an industrial product - uniquely effective combined with EDTA. Long term stability was not evaluated.

        • Abdullah

          Member
          June 7, 2024 at 5:29 am

          Thanks

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