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Solubilizing of sodium pyrrolidone carboxylic acid
Hi
would someone advise me how dissolve sodium pyrrolidone carboxylic acid in water? I have no access to the aqueous solution of Na PCA 50%. -
4 Replies
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Na PCA 50%? Isn’t that a 50% solution in water?Anyway, sodium PCA has very good solubility in water which is so good, you don’t have to bother about it because it’s likely always higher than the concentration of sodium PCA used in a cosmetic product. -
What I have the powder NaPCA, and can’t dissolve it in water. In boiling water it creates a cream-like solution. When I use polysorbate it becomes a translucent solution on the top of which is oli (I mean two phase are created), and with the passage of time, when the solution becomes cooler, the oil phase turns to the powder NaPCA:((
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Are you sure you have sodium PCA? Liquid sodium PCA 50% is a 50% solution in water. The powder/crystalline form would be 100% sodium PCA which is very hygroscopic and tends to attract water from air which leads to clumping and finally melting of the salt if you let it sit around for some time.If it doesn’t immediately dissolve in water, it’s either PCA or something else entirely. Sodium PCA isn’t soluble in polysorbates and, I don’t know but suppose, PCA wouldn’t dissolve with polysorbate either.
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Dear Pharma,
Thank you for your advice in deed. It was really helpful. It is definitely something else as per your explanation.
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