Home Cosmetic Science Talk Formulating solubility disodium EDTA in water at pH 5

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  • belassi

    Member
    March 23, 2017 at 7:24 pm

    Why don’t you just try it and see? How will you learn if you don’t experiment?

  • DRBOB@VERDIENT.BIZ

    Member
    March 23, 2017 at 8:32 pm

    great answer and how true

  • jeremien

    Member
    March 24, 2017 at 9:09 am

    i ask because i have tried it :), and i notice some
    small crystals. Since i see that many formulation have edta at 0.1%, i’m asking
    to know if it’s normal to have the final formulation with some unsolubilized
    edta. 


  • johnb

    Member
    March 24, 2017 at 9:50 am

    Water at pH 5 is not water but an acid. EDTANa2 is a salt. Adding this to an acid will form EDTA free acid or the monosodium EDTA salt. Both of these have a limited solubility in water - the free acid being effectively insoluble.

    A formulated product would normally be a complicated mixture of numerous components and crystal formation may well not occur in the presence of these, whatever the pH.

  • jeremien

    Member
    March 24, 2017 at 9:53 am

    So if i understand your point, better add the EDTA at the end, when the system can avoid formation of crystals

  • johnb

    Member
    March 24, 2017 at 10:00 am

    Possibly. I think it depends on the other components in the system.

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