• Formulating

  Solubilising Preservatives?

  Posted by Formulator on July 18, 2022 at 6:42 am

  Hi all,
  I’m currently reworking a formulation that has preservatives solubilised with a surfactant. I ascribe to a school of thought that preservatives should remain as much as possible in the water phase, where the microorganisms will proliferate. The original formulation has passed challenge testing. However, I wonder how effective preservatives are if they are solubilised within micelles.

  Any input is welcome.

  Abdullah replied 2 years, 4 months ago 4 Members · 3 Replies

  • preservative
  • stability
• 3 Replies

• 

  PhilGeis

  Member

  July 18, 2022 at 10:54 am

  Your point is a sound one and prob the effective basis for neutralizers (Lecithin and Tween) used in recovery media.

• 

  ketchito

  Member

  July 18, 2022 at 1:10 pm

  @Formulator That’s why preservatives that can be solubilized/emulsified by highly ethoxylated non ionic surfactants, are better added in an emulsion, during the cool down phase.

• 

  Abdullah

  Member

  July 19, 2022 at 6:44 am

  What is the preservative and surfactant?

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