selenium sulfide shampoo - Chemists Corner

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selenium sulfide shampoo

Posted by amitvedakar on May 9, 2018 at 9:24 am

1% selenium sulfide shampoo formulation help. any start up guidelines?

amitvedakar replied 6 years, 6 months ago 4 Members · 8 Replies
8 Replies

Gunther

Member
May 9, 2018 at 4:23 pm

Just some quick brainstorming

1 If I’m not mistaken Selenium-disulfide can stain metal containers, not sure about Stainless Steel, so maybe you’d need glass containers

2 Check your local laws

as some concentrations (like 1%) can still be sold as OTC but higher ones (like 2.5%) require prescriptions.

3 It’d be nice to have a Ketoconazole + Seleniun disulfide shampoo. Again check local laws as I believe Keto can be sold as OTC up to 2% concentration.

not sure if they can cross-react though, so you’d need to check this yourself.

4 Keep your formula simple. If possible, stick to a proven one.

You already have an active ingredient, so no need for unproven conditioners, essential oils or wild ideas that can hinder Selenium disulfide absorption, or cross-react with it.

Search for scientific studies about proven SD absorption, and just replicate the formulas used.
amitvedakar

Member
May 10, 2018 at 4:30 am

Thank you sir @Gunther.
Actually our is medicated 2.5% USP topical suspension (shampoo).
Is Bantonite useful/necessary in this product?
is Use of HPMC, Magnesium Aluminium Silicate useful?
Well i saw material Di hydrogenated Tallow Phatlic acid amide. Why this is used?
Our product is Shampoo base. so SLES, CocoBetaine and cocoamydobutone, Citric acid, Dimethicone are my main ingredients.
amitvedakar

Member
May 10, 2018 at 5:03 am

actually we made selenium sulfide + Clotrimazole shampoo.
But found clotrimazole unstable. It became blackish after a year.
amitvedakar

Member
June 3, 2018 at 8:49 am

Selenium Sulfide settled down at bottom.

My formula is as under.

Selelnium Sulfide-2.5%

SLES, COcodine, Cocobetaine Silicon oil, PG, BHT, BHA, Sod. Citrate, Citric acid,

GHPTC, Perfume , EDTA, PArabens, HPMC-0.5%, Water.
amitvedakar

Member
June 13, 2018 at 7:27 am

Can bentonite or Light Kaolin stop selenium form settling down?help.
chemicalmatt

Member
June 16, 2018 at 4:35 pm

Amit, don’t waste time using bentonite or other mineral clays. Kaolin does not suspend organic constituents, by the way, it just sits there. The best yield value is from guars or other saccharide gums (xanthan, sclerotium, etc,). You already have cationic guar in there - try upping it and co-dispersing it with hydroxymethylcellulose (“Methocel” by Dow) and the synergy may bring success. Good luck working with SeS. I’ve worked with it before - very toxic - take care there.
belassi

Member
June 16, 2018 at 8:17 pm

Ah yes, selenium. I just love the smell of burning selenium rectifiers in the morning … toxic as hell.
amitvedakar

Member
June 17, 2018 at 8:53 am

Thank you @chemicalmatt .

My current GHPTC & HPMC is 0.5% . I will increase & try.