Home Cosmetic Science Talk Formulating Paraben Alternative

  • Paraben Alternative

    Posted by Pasko on March 23, 2018 at 11:59 am

    Hi All :)
    on my custom moisturizing cream i used a blened material with Propylparaben, methylparaben, diazolidinyl urea, propylene glycol for preservative do someone tryed to replace paraben by phenoxyethanol, sorbic acid, caprylyl glycol some review approve phenoxyethanol to replace paraben. anyone can confirm ? formula has +60% of water

    JOJO91343 replied 7 years, 1 month ago 3 Members · 2 Replies
  • 2 Replies
  • OldPerry

    Professional Chemist / Formulator
    March 23, 2018 at 12:15 pm

    It depends on the formula whether you can switch out these preservatives. But you just have to try it and then conduct a preservative efficacy test to see if it works.

  • JOJO91343

    Member
    March 24, 2018 at 8:41 am

    The most frequently used Natural Preservatives I passed by are the three you already mentioned, in addition to Sodium Benzoate, Ethylhexylglycerin, Zemea Propanediol, Ethyl Lauroyl Arginate, and some others.  If you are formulating for EU Standards, watch out for Phenoxyethanol, you may try to add it in less that 1%, some standards overthere said that it’s Skin Irritant in the concentration of 1% or more.  Benzyl Alcohol is claimed to be skin irritant also.  As perry said, PET is important.  Also, when you look for Natural Preservatives from any source, try to focus on the Broad Spectrum, so you don’t get surprises in PET or in any other Microbiological Testing.  To avoid irritation claims, you may need to conduct “In Vivo” testing, it has certain rules to be conducted, especially, for gathering the Human Volunteers.

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