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Needed contact for corona virus?
Hi all, by making reaseachement I find that dettol with active ingredient Chloroxylenol kill covid-19 however I can not find the needed contact time for killing virus.
So have any one idea about or any reference thanks in advance.
@Perry @ngarayeva001 @Chemist77 @”Dr Catherine Pratt” @Dr_Sara -
9 Replies
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Covid-19 is the manifested disease, the responsible virus for said disease is called SARS-CoV-2.There’s literature stating that chloroxylenol does not kill corona viruses: CLICKThough it’s main activity is against bacteria, chloroxylenol may inactivate certain viruses at appropriate concentrations within minutes of contact time. It does perform best if used in a 70% ethanol solution… which raises the question whether there’s actually a point in adding it to ethanol if 70% ethanol alone does already a pretty good job against SARS-CoV-2. -
@Pharma it is very old study from April 1997 and actually chloroxylenol kill corona viruses according to Dettol website.
Reference https://www.dettol.co.uk/about-us/understanding-coronavirus/.
So i’am sure about it just I need to know contact time.
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@Fekher Reckitt is actually citing a study made this year about Chloroxylenol’s specific activity against SARS CoV-2 (https://www.ajicjournal.org/article/S0196-6553(20)30313-8/fulltext). If I’m not wrong, the contact time they sow is 5 min. Nevertheless, keep in mind that the study was published as a letter to the editor, and it didn’t make EPA update the list of disinfectants approved for COVID-19 (https://www.epa.gov/pesticide-registration/list-n-advanced-search-page-disinfectants-coronavirus-covid-19) nor there was a follow up study, so consider this information with care.
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@ketchito thanks however first link did not work about needed contact time according to my reaseachement it will be half and ten minutes just I want to find out the minimal needed contact time.
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From personal experience, I’d say it takes about 1 hour. That’s how long my wife needs to swipe the floor with Dettol and it works. Well, maybe it works because she stays home and stays safe and doesn’t go disco hopping and shoe shopping like the crazy kids who keep the bug alive and spreading… :smiley:Unless you test chloroxylenol on SARS-CoV-2 yourself you won’t find the answer you’re looking for, let alone on a cosmetic site.
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Review of preparations used for hand hygiene - WHO was reviewed in 2019.
https://www.ncbi.nlm.nih.gov/books/NBK144041/
Chloroxylenol - 30 sec.
https://pubmed.ncbi.nlm.nih.gov/19692148/FDA doesn’t approved Chloroxylenol yet I believe.
Canada have some products with Chloroxylenol authorized.
Dettol doesn’t officially claim killing covid-19, just implying. -
@Fekher If you check the table on that study, it mentions that in their research, contact time to inactivate (reduce of infectious virus from ≥3.0 to ≥4.7 log10) SARS-CoV-2 for PMC = para-chloro-meta-xylenol (or Chloroxylenol) is 5 min.
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Thank you @ketchito for interesting share I made message for Dettol company about my question and i’am waiting the answer just I guess for 1:20 diluation said by Dettol the needed contact time will be lower then 5 min but whatever even 5 min is acceptable.
@Pattsi Dettol does officially claim that some products with Chloroxylenol kill covid-19 take look at:
https://www.dettol.co.uk/media/8425/covid-sheet.pdf -
They claim effectiveness against the Covid-19 virus (SARS-CoV-2) not virucidal efficacy yet.
The lastest statement they gave
https://www.dettol.com.sg/illness-prevention/novel-coronavirus-2019-ncov/actives-in-leading-hygiene-products-are-99-9-effective-against-sars-cov-2-virus/
was referring to the letter @ketchito shared
https://www.ajicjournal.org/action/showPdf?pii=S0196-6553(20)30313-8
How independent can this be, it’s done by RB team.To be honest I have no doubt Dettol can kill SARS-CoV-2, it have been used in hospitals for a long time. Sorry I am way off topic.
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