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Making a phosphate buffer
Hi guys
I have a sample of disodium hydrogen phosphate. Unfortunately, I do not have its conjugated acid, which is sodium dihydrogen phosphate. Could you please advise me how can make a buffer to maintain the pH at 6.8?
Is it possible to use phosphoric acid to create the conjugated acid in situ (I mean using a little phosphoric acid that can completely react with the extra amount of disodium hydrogen phosphate to produce sodium dihydrogen phosphate by means of which the pH of a solution could buffer at pH 6.
? if so, how can I calculate that?or is it possible to use another weak acid like citric acid with disodium hydrogen phosphate to create a buffer for pH 6.8?
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1 Reply
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You can use phosphoric acid. It is possible to estimate by calculation though using a table is easier. In the end, you’d have to manually adjust anyways.You can also use citric acid instead.
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