Home Cosmetic Science Talk Formulating Is Pentalene Glycol (Bio) considered an effective broad spectrum preservative?

  • Is Pentalene Glycol (Bio) considered an effective broad spectrum preservative?

    Posted by anani1 on February 14, 2020 at 6:56 pm

    I was recently asked by a customer about a preservative called Dermosoft Pentiol Eco. INCI Pentalene Glycol. It’s a Bio version of Pentalene Glycol (by itself)  being marketed as an “all natural” preservative. It’s ECOCERT and COSMOS approved.
    After reading the available information, I have my concerns. I tend to be very sceptical of “all natural” preservatives to begin with, but I noticed that their prototype formulas contain no added actives or additives. So essentially a formula with no real preservation challenges. The percentage of recommended Dermosoft is 5% in these formulas, making it also very expensive.  In their documentation, they do seem to allude to the fact that a secondary active may need to be added, but the prototypes do not show this. 
    My question is, would this be an effective preservative in a formula with a significant amount of herbal additives, which natural formulators tend to use? 

    Your thoughts and expert input would be most appreciated.
    Thank you in advance
    SL

    LuisJavier replied 5 years ago 4 Members · 5 Replies
  • 5 Replies
  • Pharma

    Member
    February 14, 2020 at 7:24 pm
    I wouldn’t use it alone but to boost other (natural) preservatives. According to Cosphatec, it’s broad spectrum but only of moderate activity. I don’t have personal experience other than some recent playing with it. Feels nice, though :) .
    The prototype formulations you’re referring to, are they THIS and THAT one?
  • anani1

    Member
    February 14, 2020 at 8:09 pm

    Pharma said:

    The prototype formulations you’re referring to, are they THIS and THAT one?

    Thank you so much for your response. Yes, those are the prototypes that I was referring to. Do you have any suggestions for a co-preservative for this one?

    SL

  • Pharma

    Member
    February 16, 2020 at 8:48 am
    Based on theory (not practical experience), phenolics and acids should be good partners, like for example anisic and levulinic acid.
    Cosphatec has a blend with glyceryl caprylate and magnolia bark extract (Cosphaderm MultiMEG) which sounds nice and doesn’t have a low pH requirement.
  • Bill_Toge

    Professional Chemist / Formulator
    February 16, 2020 at 8:44 pm
    should be if you have a high enough dose - try it and see
    1,2-diols are antimicrobial by nature, and their activity increases as the chain length gets longer
  • LuisJavier

    Member
    February 16, 2020 at 9:05 pm

    Bill_Toge said:

    should be if you have a high enough dose - try it and see
    1,2-diols are antimicrobial by nature, and their activity increases as the chain length gets longer

    Does that mean that if I include 1,2 Hexanediol at 3% in a face cream formula paired with phenoxyethanol and benzoic acid, that the hexanediol at 3% would be overkill? 

Log in to reply.

Chemists Corner