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  Is coenzyme q10 (INCI: Ubiquinone) heat sensitive

  Posted by africanbug on February 2, 2020 at 8:54 am

  Hallo.. I’m new here, this is my first post. My question is:Is coenzyme q10 (INCI: Ubiquinone) heat sensitive? My supplier site said it is not heat sensitive and can be heated in the oil phase of formulation while another site says it is and can’t be heated above 40 degrees celcius. Can someone share any information of experience on this please?

  africanbug replied 4 years, 7 months ago 2 Members · 3 Replies
• 3 Replies

• 

  Pharma

  Member

  February 2, 2020 at 4:27 pm

  It is a stable molecule, short term heating won’t degrade it.

  It’s melting point is at about 50°C and therefore, there is no need to heat it above that temp.
• 

  africanbug

  Member

  February 3, 2020 at 1:06 pm

  Thank you very much for your information it is very much appreciated!

• 

  africanbug

  Member

  February 4, 2020 at 3:27 am

  Pharma said:

  It is a stable molecule, short term heating won’t degrade it.

  It’s melting point is at about 50°C and therefore, there is no need to heat it above that temp.

  Could you help me further on this pls.. if I were to incorporate it into a hot process emulsion, does it make sense if I take these steps:
  1. Emulsify oil and water phase at 70 degrees celcius.
  2. Melt the coenzyme in a small qty of oil ( small percentage from the oil phase) to 50 degrees celcius, then mix it into the emulsion and mix to homogénéisé?

  Or is there a better way to do this?

  Thank you again!

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