Home Cosmetic Science Talk Formulating Glycolic acid reacting with peservative

  • Glycolic acid reacting with peservative

    Posted by Nihed on January 5, 2024 at 5:19 pm

    HI , so I have a little problem. I was formulating a 7 % AHA serum and when I added the preservative (benzyl alcohol, dehydroacetic acid, aqua) at pH around 4 it precipitated forming a viscous yellowish substance at the bottom.I thought that maybe the glycolic acid reacted with the benzyl alcohol forming an ester or maybe the dehydroacetic acid became instable or something.

    Note : When I usually formulate emulsions even at pH 4 it doesn’t precipitate, it happen just with this kind of serums that include acids

    Can you please explain to me what happened if you have any idea and what preservative do you recommend for this type of formula?! Thank you in advance.

    formula:

    Water

    glycolic acid

    lactic acid

    Glycerin

    xanthan gum

    Sodium Hydroxide

    Preservative ( 1% )

    Nihed replied 11 months, 2 weeks ago 2 Members · 6 Replies
  • 6 Replies
  • PhilGeis

    Member
    January 6, 2024 at 6:06 am

    It’s associated with the addition of which preservative?

    • Nihed

      Member
      January 6, 2024 at 11:17 am

      It’s Cosgard which is a combination of benzyl alcohol and dehydroacetic acid and water

      • PhilGeis

        Member
        January 6, 2024 at 11:23 am

        It’s not that great a system anyway. Why not try something more pedestrian like benzoate/phenoxy.

  • Nihed

    Member
    January 6, 2024 at 11:44 am

    What percentage do you recommande using when combining both preservatives and is phenoxyethaol suitable for water based formulas ?

    • PhilGeis

      Member
      January 6, 2024 at 11:49 am

      Should be ok. ~ 0.5% (5000 ppm) phenoxy and 0.3% Na benzoate.

  • Nihed

    Member
    January 6, 2024 at 11:55 am

    Ok, I will try to switch the preservative and see if the problem is solved. Thank you very much for your help !!

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