• Formulating

  General Purpose test base

  Posted by belassi on June 11, 2016 at 11:48 pm

  I often find myself needing to test whether or not a given active has any apparent therapeutic effect. So as to avoid reinventing the wheel all the time, I formulated this general purpose base which accepts modest percentages of water based actives without trouble. (Just warm it to 35C and blend in)
  Perhaps it may be of use, so here it is:

  Water Q/S to 100%
  Sensoft T-75 (emollient) 6%
  Cetearyl alcohol (emulsifier) 3%
  PEG-7 glyceryl cocoate (emulsifier) 3%
  glycerine (humectant, preservative enhancer) 3%
  preservative 0.7%
  active ingredient for test (2% OK, don’t yet know upper limit)

  Another emollient could be substituted for the Sensoft, for instance Squalene. This particular formula is a thin cream, with very long flow characteristics, absorbs quickly with non-greasy finish.

  belassi replied 8 years, 6 months ago 3 Members · 3 Replies

  • emulsifier
  • formulating
• 3 Replies

• 

  PharmaSpain

  Member

  June 13, 2016 at 7:42 am

  Thanks Belassi.

• 

  OldPerry

  Member

  June 14, 2016 at 11:35 pm

  Do you have to make it fresh every time or can you just add the active ingredient and homogenize?

• 

  belassi

  Member

  June 15, 2016 at 12:16 am

  Just warm it to 35C, mix in and homogenize.

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