Home Cosmetic Science Talk Formulating Hair Garlic and hair growth

  • Garlic and hair growth

    Posted by Oladoo on August 28, 2018 at 5:39 pm

    Does garlic oil actually stimulate hair growth?

    OldPerry replied 6 years, 3 months ago 6 Members · 8 Replies
  • 8 Replies
  • belassi

    Member
    August 28, 2018 at 5:40 pm

    The problem is, the last company that tried it was sued for the inadvertent deaths of several vampires.

  • Doreen

    Member
    August 28, 2018 at 6:49 pm

    :joy: :joy:

  • OldPerry

    Member
    August 28, 2018 at 7:04 pm

    To answer the question…no

  • Gunther

    Member
    August 28, 2018 at 7:44 pm

    While there are some (low quality) studies that suggest so,
    they may not work in real life

    http://www.regrowth.com/hair-loss-forums/topic/topical-garlic-study/
    This studies alopecia areata, which may not work for general baldness.

    Interestingly a Yokohama university study used dimethylpolysiloxane (dimethicone) to grow culture hair follicles:

    Practical hair regeneration technology
    Researchers develop a method for large-scale preparation of hair producing tissues
    Date:February 1, 2018
    Source:Yokohama National University
    Summary:
    Researchers have developed a method for the mass preparation of cellular aggregates, also known as ‘hair follicle germs (HFGs)’, that may lead to a new treatment for hair loss.

    Culture vessel for the mass preparation of hair follicle germs (above). Generated hairs on the back of a mouse (below).
    Credit: Yokohama National University

    Researchers have developed a method for the mass preparation of cellular aggregates, also known as ‘hair follicle germs (HFGs)’, that may lead to a new treatment for hair loss.

    Although hair loss is not life-threatening, it troubles a substantial number of individuals all over the world, particularly in aging societies. Hair regenerative medicine has emerged as a new therapy to combat the problem. The therapy involves regenerating hair follicles, the tiny organs that grow and sustain hair. One of the more challenging obstacles to hair regenerative medicine has been the preparation of hair follicle germs, the reproductive source of hair follicles, on a large scale.
    The paper, published in the journal Biomaterials, reports the successful preparation of up to 5000 HFGs simultaneously, and reports new hair growth from the HFGs after transplantation into mice.
    “The key for the mass production of HFGs was a choice of substrate materials for culture vessel,” says the corresponding author Junji Fukuda, Professor, Yokohama National University. “We used oxygen-permeable dimethylpolysiloxane (PDMS) at the bottom of culture vessel, and it worked very well.”
    The research group further evaluated the feasibility of this method by transferring the prepared HFGs from a fabricated approximately 300-microwell array, called “HFG chip,” to generate hair follicles and hairs on the mouse body. The group confirmed black hair generation at both the back and scalp transplantation sites. The regenerated hair exhibited the typical hair cycle of murine hair.
    “This simple method is very robust and promising. We hope that this technique will improve human hair regenerative therapy to treat hair loss such as androgenic alopecia,” adds Fukuda. “In fact, we have preliminary data that suggests human HFG formation using human keratinocytes and dermal papilla cells.”

    Story Source:

    Materials provided by Yokohama National UniversityNote: Content may be edited for style and length.


    Journal Reference:

    1. Tatsuto Kageyama, Chisa Yoshimura, Dina Myasnikova, Ken Kataoka, Tadashi Nittami, Shoji Maruo, Junji Fukuda. Spontaneous hair follicle germ (HFG) formation in vitro, enabling the large-scale production of HFGs for regenerative medicineBiomaterials, 2018; 154: 291 DOI: 10.1016/j.biomaterials.2017.10.056

    https://www.sciencedaily.com/releases/2018/02/180201142853.htm

  • OldPerry

    Member
    August 28, 2018 at 9:13 pm

    Interesting paper. Perhaps may come to something in the future.

    But as far as garlic oil goes (after reading the study posted) I remain highly skeptical. 

  • Sibech

    Member
    August 29, 2018 at 9:12 pm
    @Oladoo The short answer is No.
    The slightly longer answer is: There are no well-performed studies indicating that garlic oil or extract may help on hair growth. Most of the studies are single-armed and it is tough to truly blind if people are smearing garlic on the skin (same issue with all aromatherapy studies).
    If you still demand to remain hopeful (or try to get funding for a research project) most of the studies are performed on people with alopecia areata, this effect is hypothesized in the (again poorly performed and poorly reported) articles to be caused by immunomodulating properties of diallyl disulfide or allicin.
    @Gunther By the look of it, the study was to create new follicle germs (ready to go into the neogen phase by using oxygen permeable dimethicone the substrate allowed the cells to self-assembly without interfering. Not really creating hair growth in existing follicles.
    Interesting paper none the less imagine getting a full head of hair again, without “repurposing” androgenic hair but implanting newly formed follicles.
    A ted talk about regrowing organs.

  • Oladoo

    Member
    August 30, 2018 at 11:53 am

    Thank you all for your response. How about coffee for hair growth?

  • OldPerry

    Member
    August 30, 2018 at 1:00 pm

    Coffee - no

    There is only one ingredient that has been proven to help with hair regrowth, Minoxidil. And even this doesn’t work for everyone.  All other claimed ingredients are supported only by anecdotes and small, unrepeatable studies. 

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