• Formulating

  Formulating liposomes

  Posted by HYB_88 on March 9, 2023 at 10:13 pm

  Hi all, so I am quite new to this field and am trying to figure out how to formulate liposomes to incorporate a lipophilic active ingredient. I am curious about how does one go about selecting surfactants and the levels to test out in this case please? is HLB still applicable here? Thanks in advance for your time and help!

  HYB_88 replied 1 year, 8 months ago 3 Members · 4 Replies
• 4 Replies

• 

  MarkBroussard

  Member

  March 10, 2023 at 1:38 pm

  There are a variety of techniques that can be used to formulate liposomes. Just Google it and you will find several different recipes. But, you will need the right equipment to do this.

  • 

    HYB_88

    Member

    March 30, 2023 at 2:55 am

    Thank you so much!

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  chemicalmatt

  Member

  March 14, 2023 at 4:02 pm

  I’ll second Mark’s reply here, adding that you are not to “formulate” liposomes so much as “fabricate” them. Once fabricated then you may formulate with them. As Mark says, the right equipment - and reagents - are needed. How comfortable are you handling ethyl ether? Blows up real good, I hear.

  • 

    HYB_88

    Member

    March 30, 2023 at 2:56 am

    Thanks so much for helping! Oh dear, I am not sure that we are able to handle ethyl ether. Does it have to be used to make liposomes? Or are there alternatives please?

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