Home Cosmetic Science Talk Formulating General Eyelash growth serum clearness

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  • Eyelash growth serum clearness

    Posted by ali-383 on July 24, 2024 at 12:57 am

    Hi every one it my first time chatting here, hope you all be fine and doing well.

    i have a problem with my new eyelash growth serum which i made, it contain 80% different oils like coconut, almond, argan and so on. it’s clear until you mix the water phase with the water phase don’t have water but the ingredients are water soluble like myristoyl pentapeptide-17 , biotinoyl tripeptide-1 and so one and i don’t know what can make it clear.

    ali-383 replied 1 month, 1 week ago 5 Members · 15 Replies
  • 15 Replies
  • fareloz

    Member
    July 24, 2024 at 5:00 am

    Water-soluble ingredients are water-soluble. They are not oil-soluble. Water-soluble ingredients won’t dissolve in oils, because they are water-soluble and not oil-soluble.

  • PhilGeis

    Member
    July 24, 2024 at 8:22 am

    Growth? How will you support the claim?

    • ali-383

      Member
      July 24, 2024 at 8:42 pm

      This what that came out from my research i didn’t try it by someone yet. for now it need to make it clear and smooth and for the second step i will try it by someone to check the quality

  • ali-383

    Member
    July 24, 2024 at 8:40 pm

    this is the problem dear, so i have to use emulsifier to keep them together right?
    i am wondering which emulsifier would be better, because materials are so expensive and i want to all of the to be organic

    • Perry44

      Administrator
      July 25, 2024 at 6:52 am

      There is no “natural” emulsifier that will work. You need something like a PEG but the exact ingredient you need depends on the oils you are using. Cosmetics are not natural or “organic” (as used in the world of marketing). They are synthetic creations that often require synthetic ingredients to make them work.

      • ali-383

        Member
        July 27, 2024 at 9:25 pm

        my research team recommend me Tween 80 is it okay to use, because i used tween 60 and i couldn’t get any result, phases were separated

    • Microformulation

      Member
      July 25, 2024 at 7:30 am

      Your ingredients aren’t “organic or natural,” and simply adding “natural” ingredients won’t make your product “natural or organic” overall. This can lead to greenwashing. Be cautious if you’re making claims about eyelash growth, especially in the US. In 2009 these ingredients were popular, and marketers used them to compete with Latisse. The growth from these actives was insignificant. The FDA did cite some lines; https://www.cosmeticsandtoiletries.com/regulations/claims-labeling/news/21841967/fda-issues-warning-letter-for-eyebrow-eyelash-growth-product-claims

      • ali-383

        Member
        July 27, 2024 at 9:28 pm

        i search a lot but i could find any convincible information about, can you please tell does these peptides that i am using in this formulation are not approved by FDA as cosmetic ingredient?

        thank you

        Abdul Raheem

        • PhilGeis

          Member
          July 28, 2024 at 4:02 am

          FDA does not approve cosmetic ingredients.

          • ali-383

            Member
            July 28, 2024 at 4:45 am

            So this means that peptides has approved by FDA as drug not cosmetic ingredient right?

            thanks for your helpful feedback

            Adul raheem

            • PhilGeis

              Member
              July 28, 2024 at 5:05 am

              what product would this be?

            • ali-383

              Member
              July 28, 2024 at 6:01 am

              Eyelash growth serum

            • PhilGeis

              Member
              July 28, 2024 at 6:09 am

              The specific marketed product - are you referring to Latisse and similar Bimatoprost products? These are drugs specifically approved by FDA.

            • Microformulation

              Member
              July 28, 2024 at 11:01 am

              I can only speak to US regulatory restrictions and have some extensive personal experience with these materials and formulations from many years ago.

              Most simply it comes down to the definition of a Drug versus a Cosmetic and the FDA’s Definition. Any product that would have a physiological effect or response is a drug. Over-The-Counter drugs (OTCs) have approved actives and have identified claims you can promote such as acne, hair growth, or numerous other claims. Legend Drugs (aka prescription drugs) are yet a third category. Latisse is (at least to my knowledge still) a product that requires a prescription.

              In my experience, when Latisse was being promoted aggressively to physicians and in advertising, distributors promoted these raw materials heavily. Many “entrepreneurs” tried to capitalize on Latisse’s popularity. These peptide-based products became popular. The Formulations were fairly straightforward with a dash of greenwashing. The unit fill sizes were small and there was a potential for good profits if you could sell enough units. HOWEVER, unless you wrote a very well-crafted market copy that flirted with the claims but never crossed the line, the FDA would cite you. I can recall one person who lost over 45,000 units due to an FDA Enforcement action.

              In summary, they are cosmetic raw materials with no real documented effect outside of small studies generally performed by raw material suppliers. You must rigidly adhere to the FDA limitations. The project costs must consider packaging and fill costs as they will likely contribute more to your material costs per unit than the actual product contained within.

              Again, this would vary from region to region, but I imagine the EU and online sellers would have similar requirements and limitations.

            • ali-383

              Member
              July 28, 2024 at 7:15 pm

              thank you so much dear for you helpful advice

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