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EDTA and Carbopol
While making any batch we generally start with adding EDTA to water and then polymer ….however is there any chance that addition of EDTA after neutralisation of polymer affaects viscosity.?
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10 Replies
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which polymer are you using?
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It depends a lot on other aspects of your process.
The best way to answer your question is to try it youself and see.
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EDTA is a crystalline solid, trying to introduce it after the Carbopol would merely result in the creation of suspended air bubbles while mixing…
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You can add it after the Carbopol as long as you don’t neutralize the carbomer. If you read the Technical articles, they recommend that with emulsions, you neutralize the carbomer until after emulsification. This assumes that the Carbomer is added to the continuous phase to stabilize the emulsion. In a serum (essentially a thickened simple solution), it is a moot point. You could simply neutralize last.
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Hi all Iam using Ultrez 20.What is the ideal stage to add EDTA?Should i add it to water before addition of any polymer or should i add it after polymer addition?
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Try it for yourself and find out.
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Better yet,lopamudra, don’t add any Na(x) EDTA at all if you are using any type of carbomer including Ultrez. This is an electrolyte and it WILL crash the acrylate polymer chain extension resulting in poor or no viscosity. If you have to use it for whatever reason, add it after you have hydrated the Ultrez and don’t use much of it or you will be defeating the purpose of the Ultrez.
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Have tried using it in the past and got what @chemicalmatt just mentioned. For me it’s a big no for carbomer only based formulations.
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I use EDTA in my 3 gel products (Ultrez-20) but at only 0.01%
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in my experience, 0.1% w/w disodium EDTA does thin carbomers slightly (I’ve used it with Synthalen K, Carbopol ETD 2020, Ultrez 10, 20 and 21), but if the loss proves to be unacceptable, it can be compensated by adding slightly more carbomer
in my experience, it has never had a detrimental effect on long-term stability
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