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Tagged: formalin, lotion, preservative
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Does this cationic emulsion need another anti fungal preservative?
Posted by Abdullah on October 31, 2022 at 1:09 pmThis is a lotion formula for dry skin.
10 People who have used it like it very much and couldn’t tell any difference in mildness or irritation on skin with same formula preserved with 0.5% phenoxyethanol+ 0.15% caprylhydroxamic acid instead of formalin. Changing preservative system to 0.1% formalin is a big cost saving for me.
My question is about preservation spectrum of formalin at this pH.Do i need an anti fungal preservative with 0.1% formalin in this cationic emulsion at pH 4.5 or not?
Formula
Glycerin 12%
Petrolatum 4%
Behentrimonium chloride 0.5% active
GMS 2%
Cetearyl alcohol 1%
Lactic acid 0.4% active
Fragrance 0.05%
Formalin 0.1%(370ppm formaldehyde)
Water
pH 4.5Abdullah replied 2 years ago 3 Members · 15 Replies -
15 Replies
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Abdullah said:This is a lotion formula for dry skin.
10 People who have used it like it very much and couldn’t tell any difference in mildness or irritation on skin with same formula preserved with 0.5% phenoxyethanol+ 0.15% caprylhydroxamic acid instead of formalin. Changing preservative system to 0.1% formalin is a big cost saving for me.
My question is about preservation spectrum of formalin at this pH.Do i need an anti fungal preservative with 0.1% formalin in this cationic emulsion at pH 4.5 or not?
Formula
Glycerin 12%
Petrolatum 4%
Behentrimonium chloride 0.5% active
GMS 2%
Cetearyl alcohol 1%
Lactic acid 0.4% active
Fragrance 0.05%
Formalin 0.1%(370ppm formaldehyde)
Water
pH 4.5@Abdullah At that pH and having an organic acid, you might be OK, but maybe someone with more experience could give more perspective.
Just out of curiosity, did you chek the stability of your formula under accelerated stability conditions?
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ketchito said:Abdullah said:This is a lotion formula for dry skin.
10 People who have used it like it very much and couldn’t tell any difference in mildness or irritation on skin with same formula preserved with 0.5% phenoxyethanol+ 0.15% caprylhydroxamic acid instead of formalin. Changing preservative system to 0.1% formalin is a big cost saving for me.
My question is about preservation spectrum of formalin at this pH.Do i need an anti fungal preservative with 0.1% formalin in this cationic emulsion at pH 4.5 or not?
Formula
Glycerin 12%
Petrolatum 4%
Behentrimonium chloride 0.5% active
GMS 2%
Cetearyl alcohol 1%
Lactic acid 0.4% active
Fragrance 0.05%
Formalin 0.1%(370ppm formaldehyde)
Water
pH 4.5@Abdullah At that pH and having an organic acid, you might be OK, but maybe someone with more experience could give more perspective.
Just out of curiosity, did you chek the stability of your formula under accelerated stability conditions?
Does 0.4% lactic acid have any microbial effect?
Yes it is very stable.
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You prob do need an antifungal preservative.
The question of formaldehyde is stability. That’s why the releasers. -
PhilGeis said:You prob do need an antifungal preservative.
The question of formaldehyde is stability. That’s why the releasers.Got it
What if i reduce the pH to 4 with lactic acid?
Do i still need an anti fungal?What about 0.2%(0.11% active) DMDM hydantoin at pH 4.5 or 4 as only preservative instead of formalin?
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Thanks Prob no diff - maybe little more is it places finger on orifice to close but flip top allows water and gravity-accessed particles when open.
https://journals.asm.org/doi/abs/10.1128/aem.56.5.1476-1479.1990 -
PhilGeis said:Thanks Prob no diff - maybe little more is it places finger on orifice to close but flip top allows water and gravity-accessed particles when open.
https://journals.asm.org/doi/abs/10.1128/aem.56.5.1476-1479.1990Thanks a lot
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