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Composition of Alcohol in Alcohol based sanitizers.
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@MurtazaHakim I think the DB is for Denatonium Benzoate, a common bitterant/denaturant.
I’m a little surprised at the recommendation for non denatured (just stay away from methylated stuff). Denaturants can be as simple as peppermint essential oil, it makes the alcohol much cheaper to transport/bring in.
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Is it appropriate using technical grade Isopropylol for producing Hand Sanitizer gel or liquid ??? Technical grade is a blend of ethanol and Isopropylol.
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MurtazaHakim said:Is it appropriate using technical grade Isopropylol for producing Hand Sanitizer gel or liquid ??? Technical grade is a blend of ethanol and Isopropylol.Depends… most regulatory organs of western countries only allow pharmaceutical grade. Furthermore, certain technical grades may be harmful and cause, especially if regularly used, health problems.Given that you have a grade which lacks problematic contaminants (ask supplier for specs) and you live someplace where there are really no other options (which include social distancing, clean water, and soap), than using technical grades may be better than not using anything. -
The technical grade is a blend. Would the efficacy of the product be equivalent to the one which is formulated with Pharmaceutical grade IPA ???
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Depends on the exact composition of that blend.
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The composition of the blend I worked with was 60 mass% Ethanol and 40 mass% IPA.
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It will work, even better than equal % of ethanol but less effective than equal % of IPA. If your reference product calls for 70% ethanol and you use the blend at 70% instead, it will be slightly more efficient and showing a broader antimicrobial spectrum.
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It is difficult to find Pharmaceutical Grade IPA nowadays. Major producers of Hand Sanitizers prefer Ethanol 96% in producing hand sanitizers. Is there any specific reason for preferring Ethanol over IPA ???
Furthermore which global standards are applicable for efficacy testing of hand sanitizers or alcohol hand rubs ???
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Can Extra Neutral Alcohol (ENA) with 96% v/v Ethanol be used for making hand Sanitizer in case of shortages in availability of Ethanol 99.9% ???
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MurtazaHakim said:It is difficult to find Pharmaceutical Grade IPA nowadays. Major producers of Hand Sanitizers prefer Ethanol 96% in producing hand sanitizers. Is there any specific reason for preferring Ethanol over IPA ???
Furthermore which global standards are applicable for efficacy testing of hand sanitizers or alcohol hand rubs ???
IMO IPA smells worse than ethanol does, thus a great reason to avoid the former and choose the later.
You don’t need ethanol 99.9%.
94 / 95% ethanol will do.
Pure ethanol is called ‘absolute alcohol’ is very expensive and readily absorbs water from air, becoming 95% ethanol.Many alcoholic beverage distilleries sell lots of ethanol, but you often need a business registration (your local equivalent of DBA) to be able to directly buy alcohol from them.
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