Home Cosmetic Science Talk Formulating Comedogenic Testing Lab

  • Comedogenic Testing Lab

    Posted by cb002 on July 1, 2025 at 3:23 pm

    I am in the R&D phase of a syndet bar that is geared towards lightening/brightening. I am wanting to make “noncomedogenic” claims and need a lab to conduct this testing. The lab creating the product does not have any contacts that are not “extremely expensive.” Does anyone have any labs they can refer me to for this testing?

    cb002 replied 2 weeks, 4 days ago 2 Members · 4 Replies
  • 4 Replies
  • evchem2

    Member
    July 2, 2025 at 7:38 am

    I haven’t performed this kind of testing before, but it makes sense it would be “extremely expensive”. As far as I’m aware, the testing methods for this are either on rabbit ears (obvious ethical concerns, and less obvious validity/extrapolation issues) or human subjects. You may need to substantiate that the product is not irritating before comedogenic testing which would add additional cost. These studies involve reapplication over a period of weeks which increases the cost as well.

    The term itself is loosely defined and personally, I don’t think it’s worth the cost of testing. Here are some related references that explain better:

    https://labmuffin.com/fact-check-how-to-use-comedogenicity-ratings/

    https://pmc.ncbi.nlm.nih.gov/articles/PMC8387765/

  • cb002

    Entrepreneur
    July 2, 2025 at 10:06 am

    Thank you for your response! The reason I am wanting the testing is because everyone is telling me to be careful with claims that I make without having testing to back it up. These people (that work for the lab) see a lot of lawsuits due to unsubstantiated claims. The FDA is really getting strict about claims being made so I feel like I need testing for “insurance” to avoid a lawsuit.

    • evchem2

      Member
      July 3, 2025 at 7:08 am

      I understand! You should absolutely have substantiation for claims, for both ethical and legal liability reasons. My point is that the specific claim of ‘non-comedogenic’ will probably be inherently expensive to test in any meaningful way. Like I said I haven’t had this test performed before, but CPT labs offers it if you want to get a quote https://cptclabs.com/comedogenicity-and-acnegenicity/

      • cb002

        Entrepreneur
        July 3, 2025 at 8:59 am

        Thank you! I inquired with them for a quote but they are far outside everyone else’s pricing. I have found an EU based lab for $1500 and a USA based one for $3500. The $1500 one is on human subjects and the $3500 I am having a meeting about today to learn more.

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