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Combining preservatives, how to mix, qty
Posted by MaidenOrangeBlossom on April 17, 2025 at 8:25 pmI am thinking about combining two different preservatives in order to make my products safe enough for a bigger market. What is an example of good combinations and what percentage of each is ideal? For example most of my products are bars like conditioner bars, hyaluronic acid serum and simple creams.
I have currently in my stash, optiphen, leucidal, PE9010, NeoDefend.
Example: Hyaluronic Face Serum with water, sodium hyaluronate, glycerin, panthenol, aloe.
It has to be eczema safe too. Will be packaged in an airless pump bottle.
Would a ratio of .1% NeoDefense and .9% PE9010 be adequate?
MaidenOrangeBlossom replied 2 weeks, 4 days ago 4 Members · 9 Replies -
9 Replies
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It’s not about adding more preservatives to make a product “safer.” It’s more about a preservative that is right for a particular product. And it is the product formulation and ingredients that will determine this.
“Conditioner bars”, if these are a saponified soap product, then a preservative should not be required, as saponified products (solid or liquid) are self-preserving.
And having said all of that, you still need to set up test protocols to validate this.
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Folks need to make their products safe for any market. Good idea to combine.
Here, provide formulas including pH and forget the silly Leucidal . Can’t you find Benzoate without the added Neodefend garbage?
Based on what you have - 5000 ppm (0.5%) phenoxy (either Optiphen or 9010) and 3000 ppm (0.3%) benzoate (from Neodefend) and keep the pH at 6 or less. You need a chelator - the added stuff from Neodefend will not be enough.
As Mike said, prob don;t need a preservative for the bar and please confirm the rest with testing. If you can’t, make only for your own use.
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I no longer use the leucidal or optiphen and have switched primarily to neodefend and PE 9010 due to its safety for very sensitive skin and dermatitis. But I can switch to another solution. PE9010 seems to be in most eczema products that I’ve seen and when looking for an alternative for a water based product I found that neodefend was also safer for eczema. Later I found out you can use PE 9010 for water based formulas. But I wanted to see if using multiple preservatives might increase safety. I’m using airless pumps but it may not be enough for a larger market. A lot of my customers find me because professional products weren’t helping. But I also don’t want them to experience an infection from a ‘natural’ product.
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9010 and Optiphen are just phenoxy. Cap glycol EHG are both boosters vs Gram neg’s - not aware of diff for safety.
NeoDefend is BS. It’s just overpriced Na Benzoate - as its info says “Sodium benzoate is a preservative with bacteriostatic and fungistatic properties under acidic conditions (pH should be 6 or below). Calcium gluconate is added at a very low level as an inert flow agent.”. Gluconolactone is unstable and breaks to down to gluconate that’s already in the stuff.
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Good information, so easy to get fooled with claims.
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Maybe consider a slightly different approach. What I read into your comments is…. “Two things are better than one.” Granted there can be some truth in that statement, but more likely that will lead to having redundant strengths, and redundant weaknesses. You have on the line (Dr Phil Geis) one of the world’s foremost experts in cosmetic preservation. Utilize this opportunity to garner the information you actually need. (Please know…there is nothing wrong with redundance! It should be strived for.)
Approach your questioning to Dr Geis more like this. I will start with a base of PE9010, which I know is proficient against Gram negative bacteria. Dr Geis…. What would you add (if anything) to shore up Gram positive? What would you add for the well-known weakness in the aspect of YMF?
Asking the right questions in life….is always what got me to the desired outcomes and results. 😉
And please lose the ‘L’ brand. That is just embarrassing to see that mentioned on this forum.
I came across this nice little piece I had saved a while back from some book I have….forget which one (who know…might even be from Dr Geis’s book) :
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This reply was modified 2 weeks, 5 days ago by
Graillotion.
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This reply was modified 2 weeks, 5 days ago by
Graillotion.
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This save me a lot of money and headache, thank you!
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generally, no one preservative has sufficient broad spectrum efficacy and it’s more difficult for a bug to adapt to two preservatives
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That’s very good knowledge. I was thinking two is better than one. The benchmark companies I look to use the same preservatives and combination I was leaning towards but it doesn’t necessarily mean it will work for any of my products. Pacifica is a big name eco cert type company that usually uses gentle ingredients and often uses pe 9010 and sodium benzonate. But they can also afford testing and refunds.
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This reply was modified 2 weeks, 5 days ago by
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