Home Cosmetic Science Talk Formulating Combining preservatives, how to mix, qty

  • Combining preservatives, how to mix, qty

    Posted by MaidenOrangeBlossom on April 17, 2025 at 8:25 pm

    I am thinking about combining two different preservatives in order to make my products safe enough for a bigger market. What is an example of good combinations and what percentage of each is ideal? For example most of my products are bars like conditioner bars, hyaluronic acid serum and simple creams.

    I have currently in my stash, optiphen, leucidal, PE9010, NeoDefend.

    Example: Hyaluronic Face Serum with water, sodium hyaluronate, glycerin, panthenol, aloe.

    It has to be eczema safe too. Will be packaged in an airless pump bottle.

    Would a ratio of .1% NeoDefense and .9% PE9010 be adequate?

    MaidenOrangeBlossom replied 7 hours, 55 minutes ago 3 Members · 3 Replies
  • 3 Replies
  • mikethair

    Professional Chemist / Formulator
    April 18, 2025 at 12:28 am

    It’s not about adding more preservatives to make a product “safer.” It’s more about a preservative that is right for a particular product. And it is the product formulation and ingredients that will determine this.

    “Conditioner bars”, if these are a saponified soap product, then a preservative should not be required, as saponified products (solid or liquid) are self-preserving.

    And having said all of that, you still need to set up test protocols to validate this.

  • PhilGeis

    Member
    April 18, 2025 at 5:51 am

    Folks need to make their products safe for any market. Good idea to combine.

    Here, provide formulas including pH and forget the silly Leucidal . Can’t you find Benzoate without the added Neodefend garbage?

    Based on what you have - 5000 ppm (0.5%) phenoxy (either Optiphen or 9010) and 3000 ppm (0.3%) benzoate (from Neodefend) and keep the pH at 6 or less. You need a chelator - the added stuff from Neodefend will not be enough.

    As Mike said, prob don;t need a preservative for the bar and please confirm the rest with testing. If you can’t, make only for your own use.

    • MaidenOrangeBlossom

      Member
      April 18, 2025 at 7:57 pm

      I no longer use the leucidal or optiphen and have switched primarily to neodefend and PE 9010 due to its safety for very sensitive skin and dermatitis. But I can switch to another solution. PE9010 seems to be in most eczema products that I’ve seen and when looking for an alternative for a water based product I found that neodefend was also safer for eczema. Later I found out you can use PE 9010 for water based formulas. But I wanted to see if using multiple preservatives might increase safety. I’m using airless pumps but it may not be enough for a larger market. A lot of my customers find me because professional products weren’t helping. But I also don’t want them to experience an infection from a ‘natural’ product.

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