Chlorhexidine Digluconate Gel based - Chemists Corner

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Chlorhexidine Digluconate Gel based

Posted by Kingstone on October 9, 2019 at 5:29 am

Hi everyone,

Need to know your recommendations for the best Rehodology modifier to get Gel based like carbomer for Chlorhexidine Digluconate 0.2% and Ethanol 70%.

Thx

Chemist77 replied 4 years, 11 months ago 4 Members · 3 Replies
3 Replies

Pharma

Member
October 9, 2019 at 6:33 pm

For 70% ethanol, only PVP comes to my mind (though my mind isn’t working properly, it’s been a long day at work).
Bill_Toge

Member
October 10, 2019 at 11:20 pm

try hydroxypropyl cellulose
Chemist77

Member
October 11, 2019 at 5:11 am

Agree with @Bill_Toge, I have used HPMC though and it came out pretty nice. But comparatively still on lower side of viscosity. I tried Methocel 40-202, you can try 40-101 grade which has higher viscous. But mine was alcohol free with either benzalkonium chloride or CHG.

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