Home Cosmetic Science Talk Formulating Chelator question

  • Chelator question

    Posted by francisa on May 10, 2022 at 7:29 pm

    In a shampoo formula, sodium gluconate is called for but I don’t have any. Would I be able to use tetrasodium glutamate diacetate instead? Or is there another chelating agent you recommend?

    francisa replied 2 years, 6 months ago 9 Members · 14 Replies
  • 14 Replies
  • PhilGeis

    Member
    May 10, 2022 at 10:44 pm

    Gluconate isn’t much of a chelator - use NaEDTA

  • Paprik

    Member
    May 10, 2022 at 11:44 pm

    Yeah, tetrasodium glutamate diacetate is a good chelator. And @MarkBroussard uses it. Typical usage rate is 0.2 to 0.3%.

    But as mentioned by Phil, NaEDTA’s are good option too. 

  • GeorgeBenson

    Member
    May 10, 2022 at 11:46 pm

    @Paprik does terrasodium glutamate diacetate have any incompatibilities with other ingredients that you know of?

  • francisa

    Member
    May 11, 2022 at 12:13 am

    @PhilGeis and @Paprik I used Disodium edta and found it quite difficult to dissolve in my water phase. Why is that? 

  • MarkBroussard

    Member
    May 11, 2022 at 2:50 am

    @francisa

    You should be perfectly fine using GLDA to replace Sodium Gluconate.

  • PhilGeis

    Member
    May 11, 2022 at 10:22 am

    what is your pH?

  • francisa

    Member
    May 11, 2022 at 12:01 pm

    @PhilGeis I didn’t take the pH of my water phase. If it’s too low will that affect the solubility of the Disodium edta? 

  • Adamnfineman

    Member
    May 11, 2022 at 12:28 pm

    Good morning @francisa
    Does your disodium edta dissolve in water? Have you tried dissolving it before the other ingredients?

  • KimberlyLars

    Member
    May 11, 2022 at 2:08 pm

    It will take a little while to go in but it will. Are you using more than 0.10%?

  • francisa

    Member
    May 11, 2022 at 2:38 pm

    @KimberlyLars yes I am using more than .10% 
    could that be the issue?

  • francisa

    Member
    May 11, 2022 at 2:40 pm

    @Adamnfineman I have not tried dissolving it in water first. Good idea. 

  • Pharma

    Member
    May 11, 2022 at 7:03 pm
    EDTA becomes increasingly less soluble at low pH (and vice versa); GLDA’s solubility is less pH sensitive. However, you use it at a low concentration and the main issue you’ll see is the slow speed at which they dissolve (you’re unlikely hitting solubility limits). To speed up dissolution, use a smaller amount of water with a higher pH to make a concentrated stock solution. Some shampoo ingredients come at high pH, maybe use these to dissolve the chelates (especially if you make products for your personal use) 😉 .
    BTW EDTA is often more effective (stronger binding at lower pH) whilst GLDA is better for nature in several regards.
  • Graillotion

    Member
    May 12, 2022 at 12:02 am

    Pharma said:

    EDTA becomes increasingly less soluble at low pH (and vice versa); GLDA’s solubility is less pH sensitive. However, you use it at a low concentration and the main issue you’ll see is the slow speed at which they dissolve (you’re unlikely hitting solubility limits). To speed up dissolution, use a smaller amount of water with a higher pH to make a concentrated stock solution. 

    GLDA sold by the USA re-packers is almost always coming in a liquid solution, so for the small timers…GLDA…is NO SWEAT.

    TSGD (Tetrasodium Glutamate Diacetate) | MakingCosmetics

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  • francisa

    Member
    May 12, 2022 at 2:24 am

    @Pharma thank you so much for such a thorough answer. I think I’m going to try using the GLDA.

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