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Chelator question
Posted by francisa on May 10, 2022 at 7:29 pmIn a shampoo formula, sodium gluconate is called for but I don’t have any. Would I be able to use tetrasodium glutamate diacetate instead? Or is there another chelating agent you recommend?
francisa replied 3 years, 5 months ago 9 Members · 14 Replies - 
			14 Replies
 
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Yeah, tetrasodium glutamate diacetate is a good chelator. And @MarkBroussard uses it. Typical usage rate is 0.2 to 0.3%.
But as mentioned by Phil, NaEDTA’s are good option too.
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@Paprik does terrasodium glutamate diacetate have any incompatibilities with other ingredients that you know of?
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You should be perfectly fine using GLDA to replace Sodium Gluconate.
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Good morning @francisa
Does your disodium edta dissolve in water? Have you tried dissolving it before the other ingredients? - 
It will take a little while to go in but it will. Are you using more than 0.10%?
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EDTA becomes increasingly less soluble at low pH (and vice versa); GLDA’s solubility is less pH sensitive. However, you use it at a low concentration and the main issue you’ll see is the slow speed at which they dissolve (you’re unlikely hitting solubility limits). To speed up dissolution, use a smaller amount of water with a higher pH to make a concentrated stock solution. Some shampoo ingredients come at high pH, maybe use these to dissolve the chelates (especially if you make products for your personal use) 😉 .BTW EDTA is often more effective (stronger binding at lower pH) whilst GLDA is better for nature in several regards.
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Pharma said:EDTA becomes increasingly less soluble at low pH (and vice versa); GLDA’s solubility is less pH sensitive. However, you use it at a low concentration and the main issue you’ll see is the slow speed at which they dissolve (you’re unlikely hitting solubility limits). To speed up dissolution, use a smaller amount of water with a higher pH to make a concentrated stock solution.
GLDA sold by the USA re-packers is almost always coming in a liquid solution, so for the small timers…GLDA…is NO SWEAT.
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