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C12-C15 furoates
Hello,
I’m trying to figure out if there is interest in this group for an alternative to benzoates that is a little more polar. Specifically, if there were C12-C15 furoates instead of benzoates, would this be a benefit to formulations?
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4 Replies
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What do people use Furoates for in other industries?
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Guess they are pretty extensive in pharma industry, my nephew is asthmatic and if I remember the puff he inhales has Fluticasone Furoate.
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The good scent company sells furoates (furan esters), I think they are used for scent. However, these are methyl Furoate and ethyl Furoate, so much smaller molecules. C12 - C15 benzoates are sold as emollients and anybody in this forum is far more of an expert about it than I am. What I do know is that the Hansen Solubility Parameters of these C12-C15 benzoates and those of C12-C15 furoates is very close, with the furoates being more polar, less viscous and a little more fragrant.
I am not from this field and don’t want to impose anything. I have a small company that found a way to make these furoates from natural products. We are making a variety of furoates but the C12-C15 range is very easy to make. I am just trying to see if anyone here is using benzoates and would be interested in trying these furoates in their formulations.
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I know practically nothing about furoate esters. I’m guessing, from the Wikipedia entry that says 2-furoic acid is bactericidal & fungicidal, that the fatty esters are ways of either delivering that active material slowly in a sustained manner or of allowing it to penetrate oily media & membranes. Can anyone give me any info or point me to where I can learn about them?
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